Table 5.
Comparison of hormone levels between diabetic addicted and non-diabetic addicted male and female rats. Data from seven animals in each group
| Hormones | Groups | |||||
|---|---|---|---|---|---|---|
| Male, (mean ± SEM) | Female, (mean ± SEM) | |||||
| Diabetic addicted | Non-diabetic addicted | P-Value | Diabetic addicted | Non-diabetic addicted | P-Value | |
| T3 (ng/dL) | 1.171±0.058 | 1.337±0.111 | 0.213 | 1.452±0.173 | 1.561±0.132 | 0.628 |
| T4 (μg/dL) | 29.4±2.96 | 29.191±2.928 | 0.961 | 35.114±2.084 | 34.220±2.432 | 0.785 |
| 17OH-Progesterone (ng/mL) | 0.2±0.025 | 0.217±0.022 | 0.629 | 0.968±0.230 | 0.734±0.072 | 0.364 |
| Testosterone (ng/mL) | 0.3±0.095 | 0.261±0.034 | 0.651 | 0.395±0.077 | 0.617±0.041 | 0.027* |
| DHEA-S (ng/mL) | 0.557±0.183 | 0. 480±0.081 | 0.708 | 0.072±0.016 | 0.224±0.077 | 0.1 |
The Table 5 illustrates that the mean level of testosterone was significantly reduced in female diabetic addicted rats compared to non-diabetic addicted ones (P=0.027). However, the mean levels of T3, T4, 17-hydroxyprogesterone, testosterone, and DHEA-S did not show any significant difference between male diabetic addicted and non-diabetic addicted animals (P>0.05). *Significance at 0.05 levels.