Table 2. Odds ratio for overt thyroid irAE development.

	OR/Adjusted OR (95% CI)	p
Univariate analysis
Sex (Female > Male)	2.60 (0.86–7.85)	0.090
Thyroid uptake of FDG-PET	19.91 (4.79–82.79)	< 0.001
TSH > 2.5 μIU/mL	3.06 (0.91–10.28)	0.071
Multivariate analysis
Sex (Female > Male)	1.62 (0.41–6.37)	0.493
Thyroid uptake of FDG-PET	14.48 (3.12–67.19)	< 0.001
TSH > 2.5 μIU/mL	2.68 (0.67–10.67)	0.162

Statistical analysis was performed using logistic regression model.

Results of thyroid uptake of FDG-PET and TSH were obtained before nivolumab therapy.

OR: odds ratio, CI: confidence interval