1 Functional outcome ‐ death or dependency, death or disability at end of trial |
2 |
306 |
Odds Ratio (M‐H, Random, 95% CI) |
1.05 [0.63, 1.75] |
1.1 Behavioural interventions |
2 |
306 |
Odds Ratio (M‐H, Random, 95% CI) |
1.05 [0.63, 1.75] |
2 Case fatality at end of trial |
14 |
766 |
Odds Ratio (M‐H, Random, 95% CI) |
1.00 [0.66, 1.52] |
2.1 Behavioural interventions |
2 |
306 |
Odds Ratio (M‐H, Random, 95% CI) |
0.83 [0.46, 1.51] |
2.2 Drug therapy |
3 |
148 |
Odds Ratio (M‐H, Random, 95% CI) |
1.40 [0.31, 6.28] |
2.3 Pharyngeal electrical stimulation |
4 |
215 |
Odds Ratio (M‐H, Random, 95% CI) |
0.92 [0.38, 2.26] |
2.4 Physical stimulation (thermal, tactile) |
1 |
19 |
Odds Ratio (M‐H, Random, 95% CI) |
1.05 [0.16, 6.92] |
2.5 Transcranial magnetic stimulation |
4 |
78 |
Odds Ratio (M‐H, Random, 95% CI) |
0.28 [0.03, 2.93] |
3 Length of inpatient stay (days) |
8 |
577 |
Mean Difference (IV, Random, 95% CI) |
‐2.90 [‐5.65, ‐0.15] |
3.1 Behavioural interventions |
4 |
370 |
Mean Difference (IV, Random, 95% CI) |
‐2.70 [‐5.68, 0.28] |
3.2 Pharyngeal electrical stimulation |
4 |
207 |
Mean Difference (IV, Random, 95% CI) |
‐6.05 [‐16.40, 4.31] |
4 Proportion of participants with dysphagia at end of trial |
23 |
1487 |
Odds Ratio (M‐H, Random, 95% CI) |
0.42 [0.32, 0.55] |
4.1 Acupuncture |
8 |
676 |
Odds Ratio (M‐H, Random, 95% CI) |
0.31 [0.20, 0.49] |
4.2 Behavioural interventions |
6 |
511 |
Odds Ratio (M‐H, Random, 95% CI) |
0.45 [0.28, 0.74] |
4.3 Drug therapy |
1 |
17 |
Odds Ratio (M‐H, Random, 95% CI) |
0.48 [0.07, 3.35] |
4.4 Neuromuscular electrical stimulation |
2 |
76 |
Odds Ratio (M‐H, Random, 95% CI) |
0.51 [0.18, 1.49] |
4.5 Pharyngeal electrical stimulation |
3 |
66 |
Odds Ratio (M‐H, Random, 95% CI) |
0.55 [0.15, 2.11] |
4.6 Physical stimulation (thermal, tactile) |
2 |
127 |
Odds Ratio (M‐H, Random, 95% CI) |
0.65 [0.07, 5.85] |
4.7 Transcranial direct current stimulation |
1 |
14 |
Odds Ratio (M‐H, Random, 95% CI) |
0.29 [0.01, 8.39] |
5 Swallowing ability |
26 |
1173 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.66 [‐1.01, ‐0.32] |
5.1 Acupuncture |
6 |
496 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.55 [‐1.20, 0.11] |
5.2 Behavioural intervention |
3 |
121 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.56 [‐1.07, ‐0.05] |
5.3 Drug therapy |
1 |
71 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.46 [‐0.93, 0.01] |
5.4 Neuromuscular electrical stimulation |
2 |
100 |
Std. Mean Difference (IV, Random, 95% CI) |
‐1.34 [‐3.39, 0.71] |
5.5 Pharyngeal electrical stimulation |
3 |
194 |
Std. Mean Difference (IV, Random, 95% CI) |
0.06 [‐0.22, 0.34] |
5.6 Physical stimulation (thermal, tactile) |
1 |
16 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.30 [‐1.29, 0.68] |
5.7 Transcranial direct current stimulation |
2 |
34 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.33 [‐2.22, 1.56] |
5.8 Transcranial magnetic stimulation |
8 |
141 |
Std. Mean Difference (IV, Random, 95% CI) |
‐1.29 [‐2.37, ‐0.21] |
6 Penetration aspiration score |
11 |
303 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.37 [‐0.74, ‐0.00] |
6.1 Behavioural intervention |
1 |
27 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.88 [‐1.68, ‐0.08] |
6.2 Neuromuscular electrical stimulation |
1 |
18 |
Std. Mean Difference (IV, Random, 95% CI) |
0.57 [‐0.38, 1.52] |
6.3 Pharyngeal electrical stimulation |
4 |
177 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.17 [‐0.53, 0.19] |
6.4 Transcranial magnetic stimulation |
5 |
81 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.53 [‐1.22, 0.16] |
7 Chest infection or pneumonia |
9 |
618 |
Odds Ratio (M‐H, Random, 95% CI) |
0.36 [0.16, 0.78] |
7.1 Behavioural interventions |
6 |
473 |
Odds Ratio (M‐H, Random, 95% CI) |
0.56 [0.31, 1.00] |
7.2 Drug therapy |
1 |
60 |
Odds Ratio (M‐H, Random, 95% CI) |
0.06 [0.01, 0.21] |
7.3 Neuromuscular electrical stimulation |
1 |
57 |
Odds Ratio (M‐H, Random, 95% CI) |
0.0 [0.0, 0.0] |
7.4 Pharyngeal electrical stimulation |
1 |
28 |
Odds Ratio (M‐H, Random, 95% CI) |
0.43 [0.06, 3.09] |
8 Pharyngeal transit time (seconds) |
6 |
187 |
Mean Difference (IV, Random, 95% CI) |
‐0.23 [‐0.32, ‐0.15] |
8.1 Drug therapy |
1 |
17 |
Mean Difference (IV, Random, 95% CI) |
‐0.21 [‐0.91, 0.49] |
8.2 Neuromuscular electrical stimulation |
3 |
126 |
Mean Difference (IV, Random, 95% CI) |
‐0.23 [‐0.39, ‐0.08] |
8.3 Pharyngeal electrical stimulation |
1 |
28 |
Mean Difference (IV, Random, 95% CI) |
‐0.15 [‐0.67, 0.37] |
8.4 Physical stimulation (thermal, tactile) |
1 |
16 |
Mean Difference (IV, Random, 95% CI) |
‐0.19 [‐0.34, ‐0.04] |
9 Institutionalisation |
3 |
447 |
Odds Ratio (M‐H, Random, 95% CI) |
0.75 [0.47, 1.19] |
9.1 Behavioural interventions |
2 |
306 |
Odds Ratio (M‐H, Random, 95% CI) |
0.76 [0.39, 1.48] |
9.2 Pharyngeal electrical stimulation |
1 |
141 |
Odds Ratio (M‐H, Random, 95% CI) |
0.73 [0.36, 1.48] |
10 Nutritional (albumin) |
3 |
169 |
Mean Difference (IV, Random, 95% CI) |
0.37 [‐1.50, 2.24] |
10.1 Behavioural interventions |
2 |
64 |
Mean Difference (IV, Random, 95% CI) |
0.20 [‐4.77, 5.17] |
10.2 Pharyngeal electrical stimulation |
1 |
105 |
Mean Difference (IV, Random, 95% CI) |
0.40 [‐1.62, 2.42] |