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. 2018 Oct 30;2018(10):CD000323. doi: 10.1002/14651858.CD000323.pub3

Chen 2016a.

Methods Computer‐generated random numbers by independent research staff
Assessors blinded
Participants Multi‐centre trial in China
250 participants; 148 male
100% stroke within 2 to 7 days
Dysphagia identified by bedside swallowing assessment and videofluoroscopic swallowing study
Baseline characteristics and prognostic values similar between both groups
Interventions Rx: acupuncture and conventional stroke rehabilitation care
C: conventional stroke rehabilitation care only
Duration: 3 weeks
Follow‐up: 7 weeks
Outcomes Primary outcome: NIHSS index
Secondary outcomes: FMA for motor function, rate of recovery based on BSA, VFSS, MMSE, and MoCA
Notes Exclusions: serious heart, liver, and kidney‐related diseases; blood coagulation dysfunction; inability to complete the MMSE test or bedside swallowing assessment; congenital disabilities; posterior circulation infarcts; receiving thrombolytic; participated in other clinical trials within previous 3 months; pregnant or breastfeeding
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Computer‐generated random numbers provided by independent research staff
Allocation concealment (selection bias) Low risk Random numbers placed into sequentially numbered, opaque, sealed envelopes
Blinding (performance bias and detection bias) 
 All outcomes High risk Participants and acupuncturist aware of treatment allocations. All allopathic medical staff and rehabilitation therapists blinded
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Participants and acupuncturist not blinded
Blinding of outcome assessment (detection bias) 
 All outcomes Low risk Outcome assessors blinded
Incomplete outcome data (attrition bias) 
 All outcomes High risk 5 participants lost to follow‐up; 4 discontinued intervention. Not all participants given VFSS examination
Selective reporting (reporting bias) Low risk All outcomes reported
Other bias Low risk None identified