Boccara 2003.

Methods	Single‐centre randomized controlled trial, University hospital; France
Participants	Adult participants scheduled for carotid endarterectomy and refractory peri‐operative hypotension (N = 20)
Interventions	Goal‐directed (terlipressin infused in 1 mg intravenous boluses up to 3 mg vs norepinephrine (50 mcg/mL) at initial rate of 10 mL/h, incrementally by 2 mL/h)
Outcomes	Death, stroke, myocardial ischaemias; renal failure; hospital stay For the mortality analysis, we used data on undetermined mortality
Notes	It is unclear when participants died (peri‐operative or in‐hospital) Conflict of interest not declared
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Implicitly described
Allocation concealment (selection bias)	Low risk	Envelopes
Incomplete outcome data (attrition bias) All outcomes	Low risk	Complete follow‐up
Explicit in‐/exclusion criteria	Low risk	Described explicitly
ITT‐analysis	Unclear risk	Not reported
Adequate patient description	Low risk	Reported
Identical care	Unclear risk	Not reported
Outcome description	Low risk	Reported
Physicians blinded	Unclear risk	Not reported
Outcome assessors blinded?	Unclear risk	Not reported