Malay 1999.

Methods	Single‐centre randomized controlled trial, general hospital; USA
Participants	Adult surgical and trauma participants with septic shock (N = 10)
Interventions	Fixed dose of vasopressin (0.04 U/min) vs placebo
Outcomes	24‐Hour mortality For the mortality analysis, we used data on 24‐hour mortality
Notes	Funding: not reported Conflict of interest. not reported
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Computer‐generated list
Allocation concealment (selection bias)	Low risk	Pharmacy controlled
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	Not reported
Explicit in‐/exclusion criteria	Low risk	Described explicitly
ITT‐analysis	Unclear risk	Not reported
Adequate patient description	Low risk	Adequately reported
Identical care	Unclear risk	Not reported
Outcome description	Low risk	Clear
Physicians blinded	Low risk	Reported
Outcome assessors blinded?	Low risk	Reported