Summary of findings 3. Femoral versus internal jugular insertion: short‐term catheterization for the prevention of venous thrombosis, stenosis and infection.
| Femoral versus internal jugular insertion: short‐term catheterization for the prevention of venous thrombosis, stenosis and infection | ||||||
| Patient or population: critically ill patients who were expected to require support with renal replacement therapy Settings: inpatient Intervention: Femoral versus internal jugular insertion: short‐term haemodialysis catheterization | ||||||
| Outcomes | Illustrative comparative risks* (95% CI) | Relative effect (95% CI) | No of Participants (studies) | Quality of the evidence (GRADE) | Comments | |
| Assumed risk | Corresponding risk | |||||
| Control | Femoral versus internal jugular insertion: short‐term catheterization | |||||
| Catheter‐related infectious complications ‐ Catheter colonization | Study population | RR 1.04 (0.8 to 1.36) | 637 (1 study) | ⊕⊕⊕⊝ moderate1 | ||
| 249 per 1000 | 259 per 1000 (199 to 339) | |||||
| Moderate | ||||||
| 249 per 1000 | 259 per 1000 (199 to 339) | |||||
| Catheter‐related infectious complications ‐ Catheter related bloodstream infection | Study population | RR 0.58 (0.14 to 2.4) | 637 (1 study) | ⊕⊕⊕⊝ moderate1 | ||
| 16 per 1000 | 9 per 1000 (2 to 38) | |||||
| Moderate | ||||||
| 16 per 1000 | 9 per 1000 (2 to 38) | |||||
| Catheter‐related infectious complication ‐ Subgroup Analysis for the effect of BMI on catheter colonization ‐ Highest BMI tercile (>28.4) | Study population | RR 1.69 (1.08 to 2.65) | 202 (1 study) | ⊕⊕⊕⊝ moderate1 | ||
| 220 per 1000 | 372 per 1000 (238 to 583) | |||||
| Moderate | ||||||
| 220 per 1000 | 372 per 1000 (238 to 583) | |||||
| Catheter‐related thrombotic complications ‐ Symptomatic deep venous thrombosis | Study population | RR 0.99 (0.14 to 6.98) | 736 (1 study) | ⊕⊕⊕⊝ moderate1 | ||
| 5 per 1000 | 5 per 1000 (1 to 38) | |||||
| Moderate | ||||||
| 6 per 1000 | 6 per 1000 (1 to 42) | |||||
| Catheter‐related thrombotic complications ‐ Catheter related thrombosis | Study population | RR 0.46 (0.21 to 1.01) | 151 (1 study) | ⊕⊕⊕⊝ moderate1 | ||
| 227 per 1000 | 104 per 1000 (48 to 229) | |||||
| Moderate | ||||||
| 227 per 1000 | 104 per 1000 (48 to 229) | |||||
| Immediate mechanical complications ‐ Total mechanical complications | Study population | RR 0.51 (0.29 to 0.88) | 736 (1 study) | ⊕⊕⊕⊝ moderate1 | ||
| 96 per 1000 | 49 per 1000 (28 to 84) | |||||
| Moderate | ||||||
| 96 per 1000 | 49 per 1000 (28 to 84) | |||||
| Immediate mechanical complications ‐ Major mechanical complications | Study population | RR 0.33 (0.03 to 3.16) | 736 (1 study) | ⊕⊕⊕⊝ moderate1 | ||
| 8 per 1000 | 3 per 1000 (0 to 26) | |||||
| Moderate | ||||||
| 8 per 1000 | 3 per 1000 (0 to 25) | |||||
| *The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). CI: Confidence interval; RR: Risk ratio; | ||||||
| GRADE Working Group grades of evidence High quality: Further research is very unlikely to change our confidence in the estimate of effect. Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate. Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate. Very low quality: We are very uncertain about the estimate. | ||||||
1 Unclear risk of incomplete outcome data.