2. Femoral versus internal jugular CVA routes: short‐term catheterization .

Outcome or Subgroup	Studies	Participants	Statistical Method	Effect Estimate
2.1 Catheter‐related infectious complication	1		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
2.1.1 Catheter colonization	1	637	Risk Ratio (M‐H,Random, 95% CI)	1.04 [0.80, 1.36]
2.1.2 Catheter‐related bloodstream infection	1	637	Risk Ratio (M‐H, Random, 95% CI)	0.58 [0.14, 2.40]
2.2 Catheter‐related infectious complication: Subgroup analysis for the effect of BMI on catheter colonization	1		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
2.2.1 Lowest BMI tercile (<24.2)	1	195	Risk Ratio (M‐H, Random, 95% CI)	0.67 [0.39, 1.15]
2.2.2 Middle BMI tercile (24.2‐28.4)	1	202	Risk Ratio (M‐H, Random, 95% CI)	0.89 [0.56, 1.42]
2.2.3 Highest BMI tercile (>28.4)	1	202	Risk Ratio (M‐H, Random, 95% CI)	1.69 [1.08, 2.65]
2.3 Catheter‐related thrombosis complications	1		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
2.3.1 Symptomatic deep venous thrombosis	1	736	Risk Ratio (M‐H, Random, 95% CI)	0.99 [0.14, 6.98]
2.3.2 Catheter‐related thrombosis	1	151	Risk Ratio (M‐H, Random, 95% CI)	0.46 [0.21, 1.01]
2.4 Immediate Mechanical complications	1		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
2.4.1 Total mechanical complications	1	736	Risk Ratio (M‐H, Random, 95% CI)	0.51 [0.29, 0.88]
2.4.2 Major mechanical complications	1	736	Risk Ratio (M‐H, Random, 95% CI)	0.33 [0.03, 3.16]
2.5 Leaving the studies early	1		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
2.5.1 Withdrew consent	1	750	Risk Ratio (M‐H, Random, 95% CI)	0.50 [0.05, 5.49]
2.5.2 Did not require catheterization or died before catheterization	1	750	Risk Ratio (M‐H, Random, 95% CI)	1.00 [0.14, 7.06]
2.5.3 Met exclusion criteria	1	750	Risk Ratio (M‐H, Random, 95% CI)	0.40 [0.08, 2.05]
2.5.4 Did not have a catheter culture	1	750	Risk Ratio (M‐H, Random, 95% CI)	0.87 [0.60, 1.25]