Parienti 2008.
| Methods | Allocation: Randomized, computed generated algorithm. Blinding: Evaluator blinded. Duration (mean (SD), d): Femoral group 6.2(5.5); Internal jugular group 6.9 (7.5). |
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| Participants | Diagnosis: Critically ill patients requiring catheter insertion for renal replacement therapy, with first venous catheterization and no contraindications for either femoral or jugular access. N=736. Age (mean (SD), y): Femoral group 64.5 (14.9); internal jugular group 65.3 (14.8). Sex: F 242, M 494. Setting: 9 tertiary care university medical centres and 3 general hospitals in France. |
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| Interventions | Femoral vein insertion (n=370). Internal jugular vein insertion (n=366). |
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| Outcomes | Catheter‐related infectious complications: Colonization, CRBSI, subgroup analysis for the effect of BMI on catheter colonization. Catheter‐related thrombotic complications. Mechanical complications. Leaving the study early. |
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| Notes | ||
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Random sequence generation (selection bias) | Low risk | Computed generated algorithm. |
| Allocation concealment (selection bias) | Low risk | Concealment was obtained by a centralized 24‐hour Internet or telephone service , involving a dynamic semideterminist computed generated algorithm. |
| Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | No description. |
| Blinding of outcome assessment (detection bias) All outcomes | Low risk | Evaluator‐blinded |
| Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Number of participants with catheter colonization was inconsistent with the number reported in subgroup analysis for the effect of BMI. We contacted the author in regards to this issue. The author explained that these apparent inconsistencies were the consequence of missing data at random for body mass index making it impossible for them to stratify 20 patients in the femoral group and 18 patients in the internal jugular group according to BMI. |
| Selective reporting (reporting bias) | Low risk | Reported all data. |
| Other bias | Unclear risk | No description. |