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. 2018 Oct 23;2018(10):CD003615. doi: 10.1002/14651858.CD003615.pub4

5. Adverse events reported.

Adverse event Bill 1997 Guerreiro 1997 Total
OXC PHT OXC PHT OXC PHT Total
Somnolence 41 41 24 28 65 69 134
Headache 20 27 13 14 33 41 74
Dizziness 18 22 9 21 27 43 70
Gum Hyperplasia 2 18 2 24 4 42 46
Nausea 13 16 5 7 18 23 41
Rash 12 16 4 5 16 21 37
Nervousness 2 9 2 11 4 20 24
Apathy 0 0 11 10 11 10 21
Tremor 4 10 0 0 4 10 14
Ataxia 0 0 0 13 0 13 13
Diplopia 1 11 0 0 1 11 12
Acne 9 3 0 0 9 3 12
Nystagmus 3 8 0 0 3 8 11
Abnormal thinking 0 0 5 6 5 6 11
Abdominal pain 0 0 5 4 5 4 9
Hypertricosis 0 0 0 8 0 8 8
Vomiting 0 0 0 5 0 5 5