5. Adverse events reported.
Adverse event | Bill 1997 | Guerreiro 1997 | Total | ||||
OXC | PHT | OXC | PHT | OXC | PHT | Total | |
Somnolence | 41 | 41 | 24 | 28 | 65 | 69 | 134 |
Headache | 20 | 27 | 13 | 14 | 33 | 41 | 74 |
Dizziness | 18 | 22 | 9 | 21 | 27 | 43 | 70 |
Gum Hyperplasia | 2 | 18 | 2 | 24 | 4 | 42 | 46 |
Nausea | 13 | 16 | 5 | 7 | 18 | 23 | 41 |
Rash | 12 | 16 | 4 | 5 | 16 | 21 | 37 |
Nervousness | 2 | 9 | 2 | 11 | 4 | 20 | 24 |
Apathy | 0 | 0 | 11 | 10 | 11 | 10 | 21 |
Tremor | 4 | 10 | 0 | 0 | 4 | 10 | 14 |
Ataxia | 0 | 0 | 0 | 13 | 0 | 13 | 13 |
Diplopia | 1 | 11 | 0 | 0 | 1 | 11 | 12 |
Acne | 9 | 3 | 0 | 0 | 9 | 3 | 12 |
Nystagmus | 3 | 8 | 0 | 0 | 3 | 8 | 11 |
Abnormal thinking | 0 | 0 | 5 | 6 | 5 | 6 | 11 |
Abdominal pain | 0 | 0 | 5 | 4 | 5 | 4 | 9 |
Hypertricosis | 0 | 0 | 0 | 8 | 0 | 8 | 8 |
Vomiting | 0 | 0 | 0 | 5 | 0 | 5 | 5 |