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. 2018 Oct 29;2018(10):CD012661. doi: 10.1002/14651858.CD012661.pub2

Comparison 2. Odds ratio as the effect measure for the development of T2DM.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 T2DM incidence (IFG5.6) 21 47647 Odds Ratio (Random, 95% CI) 4.15 [2.75, 6.28]
1.1 Asia/Middle East 10 34577 Odds Ratio (Random, 95% CI) 2.94 [1.77, 4.86]
1.2 Australia/Europe/North America 9 9869 Odds Ratio (Random, 95% CI) 6.47 [3.81, 11.00]
1.3 Latin America 1 1659 Odds Ratio (Random, 95% CI) 4.28 [3.21, 5.71]
1.4 American Indians/Islands 1 1542 Odds Ratio (Random, 95% CI) 3.12 [2.31, 4.21]
2 T2DM incidence (IFG6.1) 15 36866 Odds Ratio (Random, 95% CI) 6.60 [4.18, 10.43]
2.1 Asia/Middle East 7 28921 Odds Ratio (Random, 95% CI) 5.18 [2.32, 11.53]
2.2 Australia/Europe/North America 7 6334 Odds Ratio (Random, 95% CI) 8.69 [4.95, 15.24]
2.3 Latin America 1 1611 Odds Ratio (Random, 95% CI) 3.73 [2.18, 6.38]
3 T2DM incidence (IGT) 20 21552 Odds Ratio (Random, 95% CI) 4.61 [3.76, 5.64]
3.1 Asia/Middle East 6 8643 Odds Ratio (Random, 95% CI) 3.74 [2.83, 4.94]
3.2 Australia/Europe/North America 11 9165 Odds Ratio (Random, 95% CI) 5.20 [3.62, 7.45]
3.3 Latin America 2 3478 Odds Ratio (Random, 95% CI) 4.94 [3.15, 7.76]
3.4 American Indians/Islands 1 266 Odds Ratio (Random, 95% CI) 3.60 [1.40, 9.26]
4 T2DM incidence (IFG + IGT) 9 9656 Odds Ratio (Random, 95% CI) 13.14 [7.41, 23.30]
4.1 Asia/Middle East 3 4202 Odds Ratio (Random, 95% CI) 6.99 [3.09, 15.83]
4.2 Australia/Europe/North America 6 5454 Odds Ratio (Random, 95% CI) 20.95 [12.40, 35.40]
5 T2DM incidence (HbA1c5.7) 3 3468 Odds Ratio (Random, 95% CI) 4.43 [2.20, 8.88]
5.1 Asia/Middle East 1 1137 Odds Ratio (Random, 95% CI) 4.54 [2.65, 7.78]
5.2 Europe/North America 2 2331 Odds Ratio (Random, 95% CI) 4.38 [1.36, 14.15]
6 T2DM incidence (HbA1c6.0) 3 18317 Odds Ratio (Random, 95% CI) 12.79 [4.56, 35.85]
6.1 Asia/Middle East 1 11866 Odds Ratio (Random, 95% CI) 23.20 [18.70, 28.78]
6.2 Australia/Europe/North America 1 5735 Odds Ratio (Random, 95% CI) 15.60 [6.90, 35.27]
6.3 American Indians/Islands 1 716 Odds Ratio (Random, 95% CI) 5.89 [4.23, 8.20]
7 T2DM incidence (HbA1c5.7 + IFG5.6) 2 14006 Odds Ratio (Random, 95% CI) 35.91 [20.43, 63.12]
7.1 Australia/Europe/North America 1 1294 Odds Ratio (Random, 95% CI) 26.20 [16.30, 42.11]
7.2 Asia/Middle East 1 12712 Odds Ratio (Random, 95% CI) 46.70 [33.60, 64.91]