Skip to main content
. 2018 Oct 29;2018(10):CD012661. doi: 10.1002/14651858.CD012661.pub2
Study ID Mean (SD)/median (IQR)/range systolic BP, mmHg Mean (SD)/median (IQR)/range diastolic BP (SD), mmHg Smoking: current and/or past, % Medications, % Comorbidities, % Mean (SD)/median (IQR)/range FPG,
 mmol/L Mean (SD)/median (IQR)/range 2‐h glucose, mmol/L Mean (SD)/median (IQR)/range HbA1c,
 % Notes
Admiraal 2014 38
 26
 41
 41 Hypertension:
26
26
32
19
5.2
 5.3
 5.2
 5.3 Total cohort
South‐Asian Surinamese
African Surinamese
 "Ethnic Dutch"
Aekplakorn 2006 42 Hypertension: 33
Ammari 1998 Hypertension: 47
Anjana 2015 129 (21) 78 (11) 13 5.2 (0.6) 8.7 (1.4) 6.2 (0.7)
Bae 2011 113 (14) 76 (10) 5.3 (0.5) 5.4 (0.3)
Baena‐Diez 2011 33 Hypercholesterolaemia: 38 Hypertriglyceridaemia: 15
 Hypertension: 55
Bai 1999
Bergman 2016 128 (16) 84 (10) 38 5.2 (0.5) 8.6 (1.0)
Bonora 2011
Cederberg 2010 Men: 142
 Women: 142 Men: 80
 Women: 79 Men: 18
 Women: 15 Men: 5.0
 Women: 5.0 Men: 6.8
 Women: 7.0
Chamnan 2011 139 (17) 84 (11) 15 BP lowering: 21
 Corticosteroids: 4
Charles 1997 6.6 (0.8) 9.3 (0.9)
Chen 2003 38 Hypertension: 46
Chen 2017 12–24 Hypertension: 28–55 5.1–6.1 5.9–9.2 Range for i‐IFG, i‐IGT and IFG/IGT cohorts separated by < 40 years and > 60 years
Coronado‐Malagon 2009 5.9 (0.3)
Cugati 2007 146 83 5
De Abreu 2015 128 (IQR 114–140) 79 (IQR 72–86) 13 Hypertension: 43 5.3 (IQR 5.0–5.8)
Den Biggelaar 2016 141 (IQR 132–155) 83 (IQR 78–92) 18 6.0 (IQR 5.5–6.3) 8.8 (IQR 7.8–9.9) 5.8 (IQR 5.6–6.1)
Derakhshan 2016 26
Dowse 1991
Ferrannini 2009 118–128 71–78 4.9–6.4 6.7–9.5 Range for i‐IFG5.6, i‐IFG6.1, i‐IGT, IGT5.6 and IGT6.1 cohorts
Filippatos 2016 127 (17) 82 (10) 62 Hypertension: 36
Hypercholesterolaemia: 54
5.9 (0.3)
Forouhi 2007 136 (16) 82 (10) 52
Garcia 2016 58
Gautier 2010
Gomez‐Arbelaez 2015 5.2 (0.7) 6.0 (1.8) 6.5 (1.3)
Guerrero‐Romero 2006 Dyslipidaemia: 41
 Hypertension: 24 6.4 (0.6)
Han 2017 120 (17)
119 (18)
124 (18)
78 (12)
76 (12)
80 (11)
64
34
59
Hypertension:
28
27
36
5.9 (0.3)
4.8 (0.4)
5.9 (0.3)
6.1 (1.2)
8.9 (0.9)
9.3 (0.9)
5.5 (0.4)
5.5 (0.4)
5.7 (0.4)
i‐IFG5.6
i‐IGT
IFG/IGT
Hanley 2005 132 (20) 79 (10) BP lowering: 38
 Lipid lowering: 7 5.9 (0.7) 8.5 (1.7)
Heianza 2012 125 (16) 76 (11) 5.3 (0.5)   5.3 (0.3)
Inoue 1996 142 (9) 73 (7)
Janghorbani 2015 116–117 76–77 Hypertension: 20–23 5.1–61 5.9–9.2 5.1–5.3 Range for i‐IFG, i‐IGT and IFG/IGT cohorts
Jaruratanasirikul 2016 124 (15) 77 (9)
Jeong 2010 139 (21) 87 (12) 43 5.7 (0.5)
Jiamjarasrangsi 2008a 4
Kim 2005 6.4 (0.2)
Kim 2008 128/132 80/83 5.8/6.4
Kim 2014 127–129 78 20–31 Range for i‐IFG, i‐IGT, IFG/IGT and i‐HbA1c cohorts
Kim 2016a 116–120 72–75 24–25 5.1–5.9 5.3–5.8 Range for IFG and HbA1c cohorts
Kleber 2010 120 (16) 73 (13) 5.1 (1.1) 8.5 5.6 (0.7)
Kleber 2011 120 (14) 73 (12) 4.8 (0.4) 8.4 (0.6)
Ko 1999
Ko 2001 125 (21) 78 (10) 2 6.5 (0.3) 9.1 (2.1) 6.2 (0.6)
Larsson 2000 4.7/5.5/5.5 8.6/6.8/8.7
Latifi 2016 Hypertension: 40
Lecomte 2007 135 (13) 81 (10) 23 Hypertension: 48 6.4 (0.2)
Lee 2016 125 (15) 81 (11) 20 Hypertension: 22 5.9 (0.2)
Leiva 2014 134 (16) 77 (10)
Levitzky 2008 Women: 122
 Men: 127 Women: 29
 Men: 28 Antihypertensives: Women: 14
 Men: 16 Hypertension:
Women: 26
 Men: 35
Li 2003 136–138 85–87 5.4–6.4 6.8–9.1 Range for i‐IFG, i‐IGT and IFG/IGT cohorts
Ligthart 2016 145 (21) 81 (12) 50 BP lowering: 33
 Lipid lowering: 18 Stroke: 3
 CHD: 8
Hypertension: 64
Lipska 2013 140–143 54–65 5.1–6.1 5.3–5.9 Range for i‐IFG, i‐HbA1c and IFG/HbA1c cohorts
Liu 2008 Men: 126
 Women: 124 Men: 80
 Women: 77 Men: 5.3
 Women: 5.4
Liu 2014 132 (16) 82 (8) 5.8 (0.8) 9.2 (1.2)
Liu 2016
Liu 2017 128 (21) 81 (11) 37 5.9 (0.4)
Lorenzo 2003 124 75 5.3 7.6
Lyssenko 2005 140 85 (11) 6.3 (IQR 5.8–6.6) 8.3 (1.6) 5.7 (0.4)
Magliano 2008 48 6 8 5.5
Man 2017 145 (20) 80 (12) 13 Hypertension: 74
Marshall 1994 6.1 9.5
McNeely 2003 139
 137 80
 80 5.5
 5.6 9.0
 8.8 5–6 years follow‐up
10 years follow‐up
Meigs 2003
Mohan 2008 127 (19) 81 (11) 4.5 (0.6)
Motala 2003 119 (19) 78 (13) 4.6 (1.8) 6.2 (3.8)
Motta 2010
Mykkänen 1993 159 84 1 Antihypertensives: 24 Hypertension: 47 6.2 8.4
Nakagami 2016 134 (18) 82 (12) 35 6.0 (0.6) 6.0 (0.3)
Nakanishi 2004 133 (16) 81 (11) 53 Dyslipidaemia: 40
 Proteinuria: 5
 Hypertension: 35 6.4 (0.2)
Noda 2010 Men: 5.4
 Women: 5.2 Men: 5.0
 Women: 5.1
Park 2006 6.0 (0.3)
Peterson 2017 75 (11) 5.5 (0.4)
Qian 2012 126 (21) 81 (12) 5.2 (0.7) 6.1 (1.5)
Rajala 2000 Hypertension: 49
Ramachandran 1986
Rasmussen 2008 140–142 Range for IFG and IGT cohorts
Rathmann 2009 133 (19) 80 (10) 49 Lipid lowering: 11 Hypertension: 49 5.5 (0.5) 6.3 (1.7) 5.6 (0.4)
Rijkelijkhuizen 2007 139–145 84–85 Range for IFG5.6 and IFG6.1 cohorts
Sadeghi 2015 127 (21) 81 (11) 14 5.7 (0.7) 8.4 (1.5)
Sasaki 1982 5.6 (0.9) 9.0 (0.9)
Sato 2009 91 6.0 (0.6) 5.6 (0.6)
Schranz 1989 Women: 7.2
 Men: 6.2 Women: 10.8
 Men: 9.7
Sharifi 2013 130 (12) 79 (8) 5 Hypertriglyceridaemia: 48
 Hypertension: 25
Shin 1997 130 84 6.1 6.7
Söderberg 2004 125 77 27 5.5 6.5
Song 2015 123–127 76–80 2–27 Dyslipidaemia: 64–66
 Hypertension: 35–44 5.7–5.8 Ranges for male and female cohorts
Song 2016a 134 (20) 85 (12) 23 6.0 (0.4) 5.9 (1.6)
Soriguer 2008
Stengard 1992 156 88 Hypertension: 53 5.4 (1.1) 9.7 (0.8)
Toshihiro 2008 126 (12) 81 (10) 47 6.1 (0.6) 8.8 (1.3)
Vaccaro 1999 4.2 (0.8) 4.5 (1.7)
Valdes 2008 135–144 84–92 5.8–6.4 6.4–7.3 4.9–5.1 Ranges for IFG5.6 and IFG6.1 cohorts
Vijayakumar 2017 A: 5.4/C: 5.2 A: 6.7/C: 6.5 A: 5.8/C: 5.7
Viswanathan 2007 6.1 (0.7) 8.9 (1.0)
Wang 2007 124 (19) 78 (11) 28 Hypertension: 36 5.8 (0.9) 7.4 (1.7)
Wang 2011
Warren 2017 22 Hypertension: 38 6.0 (0.4) 5.6 (0.4) Data for cohort 1 (IFG5.6)
Wat 2001 126 78 5.4 8.9
Weiss 2005 5.2 8.9
Wheelock 2016 5.4 (1.2)
Wong 2003 125 74 24 5.7 8.9
Yeboah 2011 132 (21) 74 (11) 50 BP lowering: 56
 Lipid lowering (statins): 17 6.0 (0.4)
Zethelius 2004 5.7 (0.7) 7.9 (1.9)
2‐h: 2‐h measurement after an OGTT; BP: blood pressure; CHD: coronary heart disease; FG: fasting glucose; FPG: fasting plasma glucose; HbA1c: glycosylated haemoglobin A1c; HbA1c5.7/6.0: HbA1c threshold 5.7% or 6.0% (usually reflecting 5.7% to 6.4% and 6.0% to 6.4%, respectively); HbA1c/IFG: both HbA1c and IFG; i‐: isolated; IFG5.6/6.1: impaired fasting glucose (threshold 5.6 mmol/L or 6.1 mmol/L);IGT: impaired glucose tolerance; IFG/IGT: both IFG and IGT; IQR: interquartile range; OGTT: oral glucose tolerance test; SD: standard deviation