1. Comparison of reflectance confocal microscopy with dermoscopy for the detection of basal cell carcinoma.

Test	Studies	Lesions (cases)	Sensitivity (95% CI)	Specificity (95% CI)
Any suspicious lesion studies (all studies)
RCM	4	912	0.76 (0.45 to 0.92)	0.95 (0.66 to 0.99)
Dermoscopy	0	—	—	—
Any suspicious lesion studies (direct comparisons)
RCM	0	—	—	—
Dermoscopy	0	—	—	—
Equivocal lesion studies (all studies)
RCM	3	668	0.94 (0.79 to 0.98)	0.85 (0.72 to 0.92)
Dermoscopy	1	260	0.85 (0.77 to 0.91)	0.92 (0.87 to 0.96)
Equivocal lesion studies (direct comparisons)
RCM	1	260	0.85 (0.77 to 0.91)	0.94 (0.89 to 0.97)
Dermoscopy	1	260	0.85 (0.77 to 0.91)	0.92 (0.87 to 0.96)

CI: confidence interval; RCM: reflectance confocal microscopy.