3. Comparison of reflectance confocal microscopy with dermoscopy for the detection of squamous cell carcinoma.
| Test | Studies | Lesions (cases) | Sensitivity (95% CI) | Specificity (95% CI) |
| All lesion studies (all studies) | ||||
| RCM | 1 | 323 (42) | 0.74 (0.58 to 0.86) | 0.92 (0.88 to 0.95) |
| Dermoscopy | 0 | — | — | — |
| All lesion studies (direct comparisons) | ||||
| RCM | 0 | — | — | — |
| Dermoscopy | 0 | — | — | — |
| Equivocal lesion studies (all studies) | ||||
| RCM | 1 | 260 (13) | 0.77 (0.46 to 0.95) | 0.98 (0.96 to 1.00) |
| Dermoscopy | 1 | 260 (13) | 0.77 (0.46 to 0.95) | 0.99 (0.96 to 1.00) |
| Equivocal lesion studies (direct comparisons) | ||||
| RCM | 1 | 260 (13) | 0.77 (0.46 to 0.95) | 0.98 (0.96 to 1.00) |
| Dermoscopy | 1 | 260 (13) | 0.77 (0.46 to 0.95) | 0.99 (0.96 to 1.00) |
CI: confidence interval; RCM: reflectance confocal microscopy.