NTR6912.

Study name	Addition of the SUPPORT Coach in PTSD treatment
Methods	Randomised controlled trial
Participants	Inclusion criteria: Adults aged ≥ 18 years Referred to a mental healthcare institute for trauma‐focused psychotherapy for PTSD following ≥ 1 traumatic experiences Meet the DSM‐5 diagnostic criteria for PTSD as confirmed by the CAPS‐5 In possession of a mobile phone working on ANDROID/IOS operating systems Sufficient understanding of the Dutch language (speaking, writing, listening) Exclusion criteria: Current high risk for suicide according to MINI Serious psychiatric comorbidity, i.e. psychotic illness, bipolar affective disorder, substance‐related disorders, severe personality disorder, or mental retardation Not having access to a smartphone with an Internet connection
Interventions	Experimental arm SUPPORT Coach, a mobile application aiming to help people better understand and self‐manage their PTSD symptoms. The SUPPORT Coach includes psychoeducation, a self‐test with a monitoring feature, and exercises and tools to cope with PTSD symptoms Comparator arm Trauma‐focused therapy
Outcomes	Time points for assessment: post‐treatment at the 13th session Primary outcomes: PTSD symptoms (measured by the difference in PCL‐5 score reduction (continuous)) Secondary outcomes: feasibility and acceptance of the SUPPORT Coach app
Starting date	15 October 2017
Contact information	Dr M Oiff Academic Medical Center, Amsterdam m.olff@amc.uva.nl
Notes	www.amc.nl/supportcoach

AAT: Approach Avoidance Tasks; AFT: Assessment and Feedback Tool; AUD: alcohol use disorder; AUDIT: Alcohol Use Disorders Identification Test; BVI: Bochumer Change Inventory; BVMT‐R: Brief Visuospatial Memory Test – Revised; CAPS: Clinically Administered PTSD Scale; CBT: cognitive behavioural therapy; CEQ: Credibility/Expectancy Questionnaire; CIWA‐Ar: Clinical Institute Withdrawal Assessment for Alcohol; CPT: cognitive processing therapy; CPT‐II: Conners' Continuous Performance Task II; CTQ: Childhood Trauma Questionnaire; CSS: Crisis Support Scale; CWIT: Color‐Word Interference Test; DAST: ; DDT: Delay Discounting Task; DES: ; DERS: Difficulties in Emotion Regulation Scale; DES: Dissociative Experiences Scale; DEVS: Distress and Endorsement Validation Scale; DKEFS: Delis‐Kaplan Executive Functions System; DoD: Department of Defense; DSI‐SS: Depressive Symptoms Index‐Suicidality Subscale; DSM: Diagnostic and Statistical Manual of Mental Disorders; EQ‐5D: EuroQol‐5D; ERQ: Emotion Regulation Questionnaire; F20‐F29: schizophrenia, schizotypal and delusional, and other non‐mood psychotic disorders; GAD‐7: Generalised Anxiety Disorder 7 Item Scale; GSES: General Self‐Efficacy Scale; HVLT: Hopkins Verbal Learning Test; I‐CBT: Internet‐based cognitive behavioural therapy; ICD‐10: International Classification of Diseases – 10th edition; IES‐R: Impact of Events Scale – Revised; IGT: Iowa Gambling Task; IPF: Inventory of Psychosocial Functioning; ISI: Insomnia Severity Index; IUS‐12: Intolerance of Uncertainty Scale Score; K10: Kessler 10; LEC: Life Events Checklist; MINI: Mini‐International Neuropsychiatric Interview; MMSE: Mini Mental State Examination; MSPSS: Multidimensional Scale of Perceived Social Support; NEO‐FFI: NEO‐Five Factor Inventory Neuroticism scale; OEF: Operation Enduring Freedom; OIF: Operation Iragi Freedom; PCL: PTSD Checklist; PCL‐C: PTSD Checklist – Civilian; PCL‐M: PTSD Checklist – Military Version; PCT: present‐centred therapy; PE: prolonged exposure; PET: positron emission tomography; PG‐13: Prolonged Grief Disorder‐13; PHQ‐9: Patient Health Questionnaire‐9; PSS‐I: Posttraumatic Stress Disorder Symptom Scale; PTCI: Posttraumatic Cognition Inventory; PTGI: Post Traumatic Growth Inventory; PTSD: post traumatic stress disorder; PWPQ: Perceptions of Web‐PE Questionnaire; QDS: Quick Drinking Screen; Q‐LES‐Q‐SF: Quality of Life Enjoyment and Satisfaction Questionnaire Short Form; SDS: Sheehan Disability Scale; SEQ: Service Use Questionnaire; SIP: Short Inventory of Problems; STAXI‐2: State‐Trait Anger Inventory‐2; SWLS: Satisfaction With Life Scale; TBI: traumatic brain injury; TFCBT: individual trauma‐focused cognitive behavioural therapy; TLFB: Timeline Follow‐Back; TMT: trauma management therapy; VA: Veterans Affairs; VR‐12: Veterans RAND 12‐Item Health Survey; WAIS: Wechsler Adult Intelligence Scale; WCST: Wisconsin Card Sorting Test; WHODAS‐II: World Health Organization Disability Assessment Schedule; WMI: Working Memory Index; WSAS: Work and Social Adjustment Scale; WTAR: Wechsler Test of Adult Reading.