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. 2018 Nov 15;2018(11):CD003402. doi: 10.1002/14651858.CD003402.pub3

Boris 2004.

Methods Further randomisation (4 arms) of Olsen 1992 (supplementation until birth versus supplementation until 30 days after giving birth)
Participants 44 women randomised
Inclusion criteria: healthy pregnant women
Exclusion criteria: not reported
Setting: Aarhus, Denmark
Interventions SUPPLEMENTATION: omega‐3 (until birth) versus omega‐3 (continuing for 30 days after giving birth) versus olive oil versus no supplementation
Group 1: omega‐3 (1.3 g EPA and 0.9 g DHA per day) as 4 x 1 g gelatine capsules with Pikasol (Lube A/S, Hadsund, Denmark) fish oil (32% EPA (20:5n‐3), 23% DHA, and 2 mg tocopherol/mL), stopping at birth: n = 11
Group 2: omega‐3 (1.3 g EPA and 0.9 g DHA per day) as 4 x 1 g gelatine capsules with Pikasol (Lube A/S, Hadsund, Denmark) fish oil (32% EPA (20:5n‐3), 23% DHA, and 2 mg tocopherol/mL), stopping 30 days after giving birth: n = 12
Group 3: 4 x 1 g capsules of olive oil per day (72% oleic acid (18:1n‐9) and 12% LA (18:2n‐6)), stopping at birth: n = 8
Group 4: no supplement, stopping 30 days after giving birth: n = 5
Timing of supplementation: from 30 weeks GA until birth or 30 days after giving birth
DHA + EPA dose/day: high: 900 mg DHA + 1300 mg EPA
Outcomes Omega‐3 and lipid concentrations in breast milk
Notes Funding: The University of Aarhus (Aarhus, Denmark); Lube A/S ((Hadsund, Denmark), supplied Pikasol fish oil and olive oil capsules.
Declarations of interest: not reported
No outcomes able to be used in this review.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Quote: "randomly allocated"
Allocation concealment (selection bias) Unclear risk Quote: "randomly allocated"
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Partial (one group not supplemented; timing for omega‐3 groups not able to be blinded)
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Not reported
Incomplete outcome data (attrition bias) 
 All outcomes High risk 3/26 in the intervention groups and 6/18 in the control groups were lost to follow‐up (no reasons reported)
Selective reporting (reporting bias) Unclear risk Insufficient detail reported to determine confidently
Other bias Low risk Groups were similar for baseline characteristics with regard to maternal age at birth, and prepregnancy weight