Kaviani 2014.

Methods	RCT: IRCT201212101011717
Participants	80 women randomised Inclusion criteria: primiparous women > 20 weeks' gestation, with mild depression BDI score between 14 to 19, > 18 years of age, not consuming fish more than twice a week#, not suffering from schizophrenia, bipolar disorders, blood disorders, such as Von Willebrand, hypertension, hyperlipidaemia, renal and thyroid diseases, not taking anticoagulants or antidepressants, not smoking or using narcotics, or not participating in activities such as yoga, relaxation, and psychological consultations. #those consuming fish more than twice a week were replaced by the next individual Exclusion criteria: allergic or digestive reactions to study medications Setting: 2 randomly selected health centres in Shiraz, Iran
Interventions	SUPPLEMENTATION: omega‐3 versus placebo Group 1: omega‐3 LCPUFA: 1 g/day*: total number randomised = 40 Group 2: placebo (olive oil): total number randomised = 40 Timing of supplementation: women in the omega‐3 group were supplemented for 6 weeks** DHA + EPA dose/day: unclear *not further specified **gestational ages not specified apart from being > 20 weeks' gestation
Outcomes	Women/birth: depression during pregnancy (Beck Depression Inventory)
Notes	Funding: not reported Declarations of interest: none declared
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Quote: “permuted block randomisation”
Allocation concealment (selection bias)	Unclear risk	Quote: “permuted block randomisation”
Blinding of participants and personnel (performance bias) All outcomes	Low risk	Quote: “Both mothers and researchers were blinded to drug and placebo”
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Not reported
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	No losses to follow‐up reported; however women consuming fish more than twice a week were replaced by the next individual (number of instances not reported).
Selective reporting (reporting bias)	High risk	Only 1 outcome was reported.
Other bias	Unclear risk	Similar baseline characteristics except that all participants in placebo group were employed, compared with only 5% of participants in the intervention group.