Laitinen 2013.
Methods | RCT (4 arms): NCT01922791 |
Participants |
Recruitment target: 440 women. Inclusion criteria: less than 17 gestational weeks; overweight; healthy. Exclusion criteria: diabetes (Type 1 or 2); coeliac disease; increased bleeding tendency. Setting: Turku University Hospital, Finland. |
Interventions |
Intervention groups 1) probiotic dietary supplements; 2) women will receive fish oil; and 3) probiotics and fish oil (from early pregnancy until 6 months after birth, no further information provided). Control group 4) placebo (from early pregnancy until 6 months after birth). |
Outcomes |
Primary outcomes: GDM (at 24‐28 weeks' gestation; fasting glucose levels (assessed at third trimester of pregnancy); prevalence of allergy in child (at 12 and 24 months of age). Other outcomes: need for medication for management of GDM (insulin or metformin); body composition of mother (during and after pregnancy); immunologic and metabolic markers (during and after pregnancy); and faecal microbiota (during and after intervention); body composition, growth, development and metabolic markers of child 9 (0‐12 months). |
Notes | awaiting to see if there are further reports of other outcomes |