Zimmermann 2018.
| Trial name or title | Dietary supplementation of Omega 3 and the participation in the placentary vascular resistance mechanism in pregnant people |
| Methods | RCT |
| Participants | 150 pregnant women ≥ 19 years; non‐smokers |
| Interventions | women without risk factors for pre‐eclampsia: 1) 400 mg omega from 12 weeks gestation to one week prior to birth 2) no omega women at risk of pre‐eclampsia 1) AAS + 400 mg omega 2) 400 mg omega women with thrombophilia 1) heparin + 400 mg omega 2) 400 mg omega |
| Outcomes | placental vascular resistance; pre‐eclampsia; oligohydramnios; intrauterine growth restriction |
| Starting date | August 2018 |
| Contact information | Juliana Barroso Zimmermann email: julianabz@uol,com,br |
| Notes | Faculdade de Medicina de Barbacena |
Abbreviations: ADA: American Diabetes Associaton; ADORE: Assessment of DHA on Reducing Early Preterm Birth; ADP: Air Displacement Plethsmography; BDI: Beck Depression Inventory; BIS: Bioelectical Independence Spectroscopy; BMI: Body Mass Index; CMV: cytomegalovirus; DHA4PREG: DHA for PREGnant women; DHA: docosahexaenoic acid; DXA: dual x‐ray absorptiometry; EPA: eicosapentaenoic acid; EPDS: Edinburgh Postnatal Depression Scale; FOPCHIN: Fish Oil Supplementation to Pregnant Women in China; GA: gestational age; GDM: gestational diabetes mellitus; HAMD: Hamilton Rating Scale for Depression; HBV: Hepatitis B virus; HCV: Hepatitis C virus; HIV: human immunodeficiency virus; HOMA‐IR: Homeostatic Model Assessment of Insulin Resistance; hCG: human chorionic gonadotropin; IVGTT: Intravenous Glucose Tolerance Test; LCPUFA: long‐chain polyunsaturated acids; MDD: major depressive disorder; MINI: Min‐International Neuropsychiatric Interview; NHMRC: National Health and Medical Research Institute; NICU: neonatal intensive care unit; NSAIDs: nonsteroidal anti‐inflammatory drugs; OGTT: oral glucose tolerance test; PUFA: polyunsaturated fatty acid; RCT: randomised controlled trial; SAHMRI: South Australian Health and Medical Resesarch Institute; SYNCHRO:The Synchronized Trial on Expectant Mothers with Depressive Symptoms by Omega‐3 PUFAs; UBC: umbilical cord blood