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. 2018 Dec 19;2018(12):CD012470. doi: 10.1002/14651858.CD012470.pub2

Summary of findings 2. Summary of findings. Bandage versus cast.

Bandage versus below‐elbow cast for buckle or minimally displaced fracture in children
Patient or population: children with stable wrist fracture, predominantly buckle (torus) fracturesa
Settings: hospital clinic
Intervention: Soft or elasticated bandageb for 3 to 4 weeks
Comparison: Below‐elbow cast for 3 to 4 weeks
Outcomes Illustrative comparative risks* (95% CI) Relative effect
 (95% CI) No of Participants
 (studies) Quality of the evidence
 (GRADE) Comments
Assumed risk Corresponding risk
Below‐elbow cast Bandage
Physical function (short‐term): no problems or only 'limited disability' (see Comments) (4 to 6 weeks follow‐up) 500 per 1000c 895 per 1000 (590 to 1000) RR 1.79
 (1.18 to 2.73) 53 (1 study) ⊕⊝⊝⊝
 very lowd 'Limited disability' applied to 1 of 5 areas: interference with play; help needed with feeding; help needed with washing and dressing; sleep disturbance; missed days of school
Treatment failure:
(3 to 6 weeks follow‐up)
33 per 1000e 51 per 1000 (15 to 176) RR 1.53 (0.44 to 5.32) 181 children
(3 studies)
⊕⊝⊝⊝
 very lowf Parents of 4 children (4.4%) requested a change from bandage to cast; 3 because they were sore from overuse and 1 "special needs" child. There were no requests for change in the cast group.
1 trial reported 4 cases (1 in the bandage group versus 3 in the cast group) of delayed union requiring an extra week
Serious adverse events
(3 to 4 weeks follow‐up)
See comment See comment Not estimable 139 children
 (2 studies) See comment No children developed a serious adverse event, including refracture, in these 2 studies.
 This is consistent with other evidence, including from other included trials with buckle fractures that explicitly reported the absence of serious adverse events (87 children from 1 study comparing removable splint versus cast; 288 children from 1 study comparing home versus hospital removal of casts)
Time to return to former activities See comment See comment Not estimable See comment This outcome was not reported
Pain with VAS (0 to 100; worst pain) at 1 week The mean score in the study control group was 20 The mean score in the intervention group was
 6 higher (1.31 lower to 13.31 higher) 89 children
 (1 study) ⊕⊝⊝⊝
 very lowg The 95% CI is unlikely to include a clinically important effect. There was also very low‐quality evidence of less pain in the bandage group in 1 study (39 children), and little difference in pain during device use or requirement for analgesic in another study (53 participants)h
Minor complications
(3 to 6 weeks follow‐up)
See comment See comment Not estimable 92 children
 (2 studies)
(individual complications)
See comment Complications reported were skin problems, increased deformity (minimal) and stiffnessi. Where reported, there was very low‐quality evidence of little or no difference between groups in the individual complications
Participant satisfaction: children found treatment was convenient
(4 weeks follow‐up)
143 per 1000c 946 per 1000
 (331 to 1000) RR 6.61
(2.31 to 18.96)
39 children
(1 study)
⊕⊝⊝⊝
 very lowj In this study, all 18 participants followed up in the bandage group had removed their bandage by 2 weeks
*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
 CI: Confidence interval; RR: Risk Ratio; VAS: visual analogue scale
GRADE Working Group grades of evidence
 High quality: Further research is very unlikely to change our confidence in the estimate of effect.
 Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.
 Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.
 Very low quality: We are very uncertain about the estimate.

aChildren had buckle fractures in two studies, "impacted greenstick" fractures in one study and either buckle or an "undisplaced greenstick" fracture in one study.
 bThe soft bandage was a wool layer covered with a cotton crepe bandage. The elasticated bandage was a tubigrip.
 cControl group risk is derived from the study data.
 dWe downgraded the evidence by two levels for very serious risk of bias, mainly reflecting lack of blinding (performance and detection biases), and by one level for serious indirectness for an inadequately reported outcome measure.
 eControl group risk is derived from the mean, since the median control risk (as in 2 studies) = 0.
 fWe downgraded the evidence by two levels for very serious risk of bias, mainly reflecting lack of blinding (performance and detection biases), and by two levels for very serious imprecision (few events, wide confidence interval).
 gWe downgraded by two levels for very serious risk of bias, reflecting lack of blinding (performance and detection biases), and by one level for imprecision for wide confidence intervals.
 hPain was measured in different ways: one study referred to a "semantic scale", one used a VAS and also reported in terms of requiring analgesics.
 iOne study (39 children) reported an absence of skin problems; and one study (53 children) reported one child in each group had slightly increased deformity; the same trial found three children in the cast group had stiffness after cast removal. The data from one study (49 children) reporting four cases of delayed union requiring extended treatment are included under treatment failure.
 jWe downgraded by two levels for very serious risk of bias, reflecting lack of blinding (blinding and performance biases), by one level for serious imprecision reflecting the small sample size, and by one level for serious indirectness as the outcome was not a full measure of satisfaction.