Shen 2014.

Methods	Randomised to two drugs. (aimed to assess the add‐on effect of itopride to azintamide.Single‐centre. Criteria for FD: Rome III and assessed only abdominal distension.(PDS)
Participants	N = 80 Female 41% Mean age: 57.42 years for the intervention group and 64.17 years for the control group (P > 0.05) Country of study: China
Interventions	Intervention: itopride one tablet three times a day + azintamide three times a day (no dose provided) Comparator: azintamide three times a day (no dose provided) Rescue medication: azintamide Duration of treatment: 2 weeks
Outcomes	Physicians assessed abdominal distension, duration 0 to 3 scores, severity 0 to 3
Notes	Mean age was significant different between two groups Article In Chinese
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Randomly
Allocation concealment (selection bias)	Unclear risk	No information
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	No information
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	No information
Incomplete outcome data (attrition bias) All outcomes	Low risk	No dropouts
Selective reporting (reporting bias)	Low risk	Reported all pre‐defined outcomes
Other bias	Low risk	No other risk found