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. 2016 Apr 19;2016(4):CD005220. doi: 10.1002/14651858.CD005220.pub2

2. Summary table of included studies.

Review Manager ID Study design Agent Route Child.
(< 12 yrs)
Adolesc.
(12‐17 yrs)
Mean age No % Female
Paracetamol
Hämäläinen 1997a Cross‐over PO Yes Yes 10.7 80 50%
Ibuprofen
Hämäläinen 1997a Cross‐over PO Yes Yes 10.7 78 50%
Lewis 2002 Parallel PO Yes No 9.0 84 ND
Evers 2006 Cross‐over PO Yes Yes 13.9 29 56%
Triptans (< 12 years)
Ho 2012 Parallel Rizatriptan PO Yes NA ND 200 44%
Ueberall 1999 Cross‐over Sumatriptan IN Yes No 8.2 14 50%
Hämäläinen 2002 Cross‐over Sumatriptan IN Yes No 9.7 59 54%
Triptans (12‐17 years)
Linder 2008 Parallel Almotriptan PO No Yes 14.4 714 60%
Winner 2007 Parallel Eletriptan PO No Yes 14.0 274 57%
Rothner 1997 Parallel Naratriptan PO No Yes 14.3 300 54%
Ho 2012 Parallel Rizatriptan PO NA Yes ND 570 61%
Visser 2004a Parallel Rizatriptan PO No Yes 14.2 476 55%
Winner 2002 Parallel Rizatriptan PO No Yes 14.0 296 54%
Ahonen 2006 Cross‐over Rizatriptan PO Yes Yes 12.0 116 54%
Callenbach 2007 Cross‐over Sumatriptan IN No Yes 13.6 46 78%
Rothner 1999b Parallel Sumatriptan PO No Yes 13.6 92 52%
Winner 2000 Parallel Sumatriptan IN No Yes 14.1 507 52%
Hämäläinen 1997b Cross‐over Sumatriptan PO Yes Yes 12.3 23 52%
Rothner 1999c Parallel Sumatriptan PO No Yes 13.5 102 42%
Fujita 2014 Parallel Sumatriptan PO Yes Yes 14.1 144 58%
Winner 1997 Cross‐over Sumatriptan PO No Yes 13.9 298 58%
Winner 2006 Parallel Sumatriptan IN No Yes 14.3 731 55%
Ahonen 2004 Cross‐over Sumatriptan IN Yes Yes 12.4 94 46%
Rothner 1999a Parallel Sumatriptan PO No Yes 14.1 273 57%
Derosier 2012 Parallel Sumatriptan and
Naproxen Sodium
PO No Yes 14.7 490 59%
Lewis 2007 Cross‐over Zolmitriptan IN No Yes 14.2 171 57%
Evers 2006 Cross‐over Zolmitriptan PO Yes Yes 13.9 29 56%
Rothner 2006 Parallel Zolmitriptan PO No Yes 14.2 696 59%
NCT01211145 Parallel Zolmitriptan IN No Yes 14 584 ND
Dihydroergotamine
Hämäläinen 1997c Cross‐over PO Yes Yes 10.3 13 38%

IN: intranasal; NA: not applicable; ND: no data available; No: total number in efficacy analysis (intention‐to‐treat when available); PO: per os (by mouth).