Study	Reason for exclusion
Brousseau 2004	The Emergency Department setting and parenteral interventions studied (intravenous prochlorperazine versus ketorolac) were significantly different from included clinical trials of interventions in the outpatient setting. As there were few other clinical trials in the Emergency Department setting, we made a post hoc decision to exclude this study to simplify the review conclusions.
Cady 2011	Non‐drug clinical trial and participants were not exclusively pediatric
Gertsch 2011	Open‐label, uncontrolled study
NCT00355394	The Emergency Department setting and parenteral intervention studied (intravenous metoclopramide) was significantly different from included clinical trials of interventions in the outpatient setting. As there were few other clinical trials in the Emergency Department setting, we made a post hoc decision to exclude this study to simplify the review conclusions.
Soriani 2001	A non‐placebo‐controlled randomized study comparing paracetamol and nimesulide. Each of 60 participants in the study treated 10 attacks, and the primary outcome of headache relief was reported as a percentage of attacks. No individual participant data was reported so was not included in the meta‐analysis.
SUM40090	Open‐label, uncontrolled study
Trautmann 2010	Non‐drug clinical trial
Winner 2011	Study of rapid disintegrating formulation of sumatriptan was not a randomized controlled trial