Three or more basic features: Pruritus Typical morphology and distribution: Flexural lichenification or linearity in adults Facial and extensor involvement in infants and children Chronic or chronically‐relapsing dermatitis Personal or family history of atopy (asthma, allergic rhinitis, atopic dermatitis)
Plus 3 or more minor features:
Xerosis Ichthyosis/palmar hyperlinearity, keratosis pilaris Nipple eczema Cheilitis Recurrent conjunctivitis Dennie‐Morgan infraorbital fold Keratoconus Anterior subcapsular cataracts Orbital darkening Facial pallor, facial erythema Pityriasis alba Anterior neck folds White dermatographism, delayed blanch	Immediate (type 1) skin test reactivity Elevated serum IgE Early age of onset Tendency toward cutaneous infections (especially S. aureus & HSV), impaired cell‐mediated immunity Tendency toward non‐specific hand or foot dermatitis Itch when sweating Intolerance to wool or lipid solvents Perifollicular accentuation Food intolerance Course influenced by environmental or emotional factors (or both)