NCT02930941.
Trial name or title | Topical intranasal tranexamic acid for epistaxis in the emergency department |
Methods | Randomised, double‐blind, single‐centre, placebo‐controlled trial |
Participants | Adults (> 18) with anterior epistaxis |
Interventions | Intervention group: tranexamic acid (100 mg/1 mL) sprayed in to the affected nostril(s) via intranasal atomisation device; may repeat 2 doses in each affected nostril(s) Comparator group: 0.9% sodium chloride (1 mL) |
Outcomes | Primary outcome measure: Time to control of bleeding (7 days) Secondary outcome measures: Length of stay in the emergency department Re‐bleeding within the first 24 hours Re‐bleeding within the first week Incidence of thromboembolic events (7 days) Incidence of drug‐related events (7 days) |
Starting date | February 2016 |
Contact information | Principal investigator: Aimee Moulin MD, University of California, Davis (akmoulin@ucdavis.edu) |
Notes | Estimated study completion date: December 2019 |