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. 2014 Jun 10;2014(6):CD009235. doi: 10.1002/14651858.CD009235.pub3

Liu/Qui 2010.

Trial name or title Effect of NAVA on duration of weaning in difficult to wean patients
Methods Randomized controlled trial
Participants Intubated patients deemed ready for extubation by the clinical team but who fail the first spontaneous breathing trials (SBT) or weaning attempt.
Interventions Intervention: Neurally adjusted ventilatory assist (NAVA)
Control: Pressure Support Ventilation weaning
Outcomes Duration of weaning was defined as time from study enrolment to extubation
Extubation rate defined as the percentage of patients with successful weaning
Diaphragmatic function was measured by neuro‐ventilatory efficiency (NVE), a ratio of tidal volume to diaphragm electrical activity (Vt/EAdi), and neuro‐mechanical efficiency (NME), a ratio of airway pressure to EAdi(Paw/EAdi) during airway occlusion
Patient ventilator asynchrony (time delay between neuro‐inspiration and ventilator delivery. Time delay between neuro expiration and ventilator cycle‐off)
Starting date December 2010
Contact information Ling Liu +86‐25‐83272201 liuling6600@yahoo.com.cn; Haibo Qiu +86‐25‐83272200 haiboq2000@yahoo.com.cn, Nanjing Zhong‐Da Hospital, Nanjing, Jiangsu, China
Notes NCT01280773