Liu/Qui 2010.
Trial name or title | Effect of NAVA on duration of weaning in difficult to wean patients |
Methods | Randomized controlled trial |
Participants | Intubated patients deemed ready for extubation by the clinical team but who fail the first spontaneous breathing trials (SBT) or weaning attempt. |
Interventions | Intervention: Neurally adjusted ventilatory assist (NAVA) Control: Pressure Support Ventilation weaning |
Outcomes | Duration of weaning was defined as time from study enrolment to extubation Extubation rate defined as the percentage of patients with successful weaning Diaphragmatic function was measured by neuro‐ventilatory efficiency (NVE), a ratio of tidal volume to diaphragm electrical activity (Vt/EAdi), and neuro‐mechanical efficiency (NME), a ratio of airway pressure to EAdi(Paw/EAdi) during airway occlusion Patient ventilator asynchrony (time delay between neuro‐inspiration and ventilator delivery. Time delay between neuro expiration and ventilator cycle‐off) |
Starting date | December 2010 |
Contact information | Ling Liu +86‐25‐83272201 liuling6600@yahoo.com.cn; Haibo Qiu +86‐25‐83272200 haiboq2000@yahoo.com.cn, Nanjing Zhong‐Da Hospital, Nanjing, Jiangsu, China |
Notes | NCT01280773 |