Faytrouny 2007.

Methods	Parallel group RCT Funding: not stated Location: Turkey
Participants	Inclusion criteria: unco‐operative fearful healthy children, ASA I, requiring sedation due to Frankl score of definitely negative or negative n = 30, 14 females, 16 males Mean age (SD) months: Group 1 (n = 15), 61.9 (11.9) Group 2 (n = 15), 53.7 (12.8)
Interventions	Group 1: hydroxyzine (20 mg 24 hours before) + hydroxyzine (3.7 mg/kg at the appointment) Group 2: hydroxyzine (3.7 mg/kg at the appointment) All oral
Outcomes	Houpt
Notes	20 mg/kg as stated in the text a mistake as this appears to be high. 20 mg in the abstract, presumably this is the correct value 50:50 nitrous oxide/oxygen given to all participants Pediwrap used after sedation achieved
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	"Subjects were assigned randomly" ‐ method of sequence generation not described
Allocation concealment (selection bias)	Unclear risk	Not described
Blinding ‐ Participant	High risk	Drugs given at home by parents or administered at clinic by the assistant
Blinding ‐ Operator/sedationist	Low risk	Quote: "Blinded to subject group assignment"
Blinding ‐ Outcome assessor	Unclear risk	Outcomes assessed by the "monitoring dentist." Unclear whether this person was blinded to treatment
Incomplete outcome assessment	High risk	Numbers evaluated not stated
Free of selective reporting	Low risk	All planned outcomes reported
Free of other bias	Low risk	No other bias