Park 2006.

Methods	Parallel Location: South Korea Funding: not stated
Participants	Inclusion criteria: ASA I, under 6 years, 20 kg body weight, unco‐operative requiring sedation for dental treatment Mean age in months (SD), gender, mean weight in kg (SD): Group 1 (n = 15), 44.5 (14.1), 6 males and 9 females, 15.6 (2.7) Group 2 (n = 16), 34.3 (9.3), 11 males and 5 females, 15.1 (2.6)
Interventions	Group 1: chloral hydrate (60 mg/kg) + hydroxyzine (1 mg/kg). Both oral Group 2: chloral hydrate (60 mg/kg) (oral) + hydroxyzine (1 mg/kg) (oral) + midazolam (0.1 mg/kg) (submucosal) Administered by dentist
Outcomes	Houpt, requirement for restraint
Notes	50% nitrous oxide/oxygen administered to all
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Not described
Allocation concealment (selection bias)	Unclear risk	Not described
Blinding ‐ Participant	High risk	Not blinded
Blinding ‐ Operator/sedationist	High risk	Not blinded
Blinding ‐ Outcome assessor	Low risk	Video used, assessor blinded
Incomplete outcome assessment	Low risk	All outcomes reported
Free of selective reporting	Low risk	Data from all subjects reported
Free of other bias	Low risk	No other bias detected