Methods |
Ancillary study. Off‐shoot of KETASED study which was an RCT comparing ketamine and etomidate |
Participants |
n = 310. Patients who underwent pre‐hospital RSI, and who had ACTH stimulation test within 24 h or ICU admission |
Interventions |
Patients in the KETASED study were randomized to ketamine or etomidate. This study groups patients as having RAI or not, and then identifying risk factors based on this grouping, not on whether they received etomidate or ketamine |
Outcomes |
The objective of this study was to assess the effect of relative adrenal insufficiency (RAI) on prognostic outcomes after RSI, and factors associated with the onset of RAI |
Notes |
This was the same population as the Jabre 2009 study. This sample size is larger because this report includes the patients who were excluded by Jabre who had died before arrival to hospital, or who were discharged from the ICU before the 3 day mark |