AC Omega3.
Trial name or title | The Aboriginal cardiovascular omega‐3 randomised controlled trial (AC Omega3) |
Methods | RCT |
Participants | Indigenous Australian adults with stable coronary artery disease |
Interventions | Each for 12 months: Arm 1: omega‐3 (1800 mg/d AlaskOmega: 3 capsules/d: 400 mg EPA and 200 mg DHA) Arm 2: placebo mixed oil capsules (1000 mg/d: 3 capsules/d containing palm oil, gelatin, glycerol, sunflower oil, rapeseed oil, mixed tocopherols, and a "small amount" of fish oil ((or taste) to aid blinding) |
Outcomes | Primary: serum non‐HDL cholesterol Secondary: triglycerides, total cholesterol, LDL, HDL, lipid functionality by cholesterol efflux and CETP, heart rate variability, platelet function and thrombosis markers, inflammation markers, cumulative combined rate of major adverse cardiac events (including death, non‐fatal MI, unstable angina, non‐fatal stroke, revascularisation and cardiac‐related hospital admissions) |
Starting date | Registered on Trials Registry: 10 July 2014 Trial start date: 1 October 2014 Trial completion date est: unclear |
Contact information | Alex Brown (PI), Wardliparingga Aboriginal Unit, Adelaide, Australia, alex.brown@sahmri.com |
Notes | ACTRN12614000732684 Alex Brown contacted in 2016: confirmed trial is actively recruiting |