NCT02676466.

Trial name or title	Enabling reduction of low‐grade inflammation in seniors (ENRGISE)
Methods	RCT
Participants	People aged 70+ years with self‐reported walking or stair‐climbing difficulty
Interventions	Each for 1 year Arm 1: omega‐3 fish oil (1.4 g/d for 6 months, possibly increasing to 2.8 g/d) Arm 2: losartan 25 mg/d Arm 3: placebo corn oil (for omega‐3) plus placebo cellulose (for losartan) Arm 4: omega‐3 plus losartan Arm 5: placebo corn oil (for omega‐3) Arm 6: placebo cellulose (for losartan)
Outcomes	Primary: IL6, 400‐meter walk test Secondary: short physical performance battery, frailty, hand grip strength, knee dynamometry, Short Form (SF)‐36
Starting date	Registered on Trials Registry 3 February 2016 Trial start date: February 2016 Trial completion date est: March 2018
Contact information	Jane Lu janelu@ufl.edu Michael Stancil mstancil@ufl.edu
Notes	NCT02676466