(please circle)
Type of study Can the study be described as randomized?	Yes, Unclear, No
Participants 1. Were the participants adults (at least 18 years & over) and in ICUs? 2. Were participants intubated (naso/orotracheal) and receiving invasive mechanical ventilation (MV)?	Yes, Unclear, No Yes, Unclear, No
Interventions 1. Was one group weaned using a formal weaning protocol1? 2. Was the other group weaned without reference to a formal protocol?	Yes, Unclear, No Yes, Unclear, No
Outcomes: Did the study report any one of – 1. Total duration of MV (time from initiation of MV to MV discontinuation)? 2. Weaning duration (time from identification of weaning readiness to MV discontinuation)? 3. ICU length of stay	Yes, Unclear, No Yes, Unclear, No Yes, Unclear, No
Conclusion: Do not proceed if any of the above answers are ‘No’. If study to be ‘included’ or ‘excluded & listed in excluded table’, record below the information to be inserted into tables. If included – continue to page 2 Included, or Excluded and should be listed in the excluded table More information needed before inclusion decision (specify): Record for tables: