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. 2004 Oct 18;2004(4):CD004477. doi: 10.1002/14651858.CD004477.pub2
Methods n = 36
Allocation concealment: not described
Baseline similarity: not described
Blinding: caregivers not blinded (no placebo)
Cointerventions: not described
Withdrawals: none
Losses to follow‐up: none
Participants Patients with ALI/ARDS (not described)
Interventions Intratracheal porcine surfactant (HL10) with 100‐200 mg/kg of phospholipids, up to 4 doses, or standard therapy
Outcomes 28 day mortality: RR 0.21 (95% CI 0.05 to 0.91)
Ventilator free days to day 28: MD 0.80 (95% CI ‐6.33 to 7.93)
Notes Published only as abstract
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) Unclear risk B ‐ Unclear