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. 2018 Oct 30;2018(10):CD009764. doi: 10.1002/14651858.CD009764.pub3

1.7. Analysis.

Comparison 1 Antibiotics versus placebo, Outcome 7 COPD exacerbations according to severity of COPD ‐ continuous antibiotics.

COPD exacerbations according to severity of COPD ‐ continuous antibiotics
Study Gold stage Rate of exacerbations per patient year on azithromycin (Mean +/‐ SD) Rate of exacerbations per patient year on placebo (Mean +/‐ SD)
Albert 2011 2 : FEV1 (80% ‐ 50%) 1.02 (+/‐ 0.15) 1.68 (+/‐ 0.16)
Albert 2011 3 : FEV1 (50% ‐ 30%) 1.53 (+/‐ 0.13) 1.75 (+/‐ 0.13)
Albert 2011 4 : FEV1 < 30% 1.75 (+/‐ 0.12) 2.05 (+/‐ 0.28)