Argentina 1987.

Methods	Allocation concealment: not stated. Authors state "open randomised study". Two arms.
Participants	20 women with SBP > 159 mmHg and/or DBP > 99 mmHg x 2, 24 hrs apart, +/‐ proteinuria. Excluded: > 1 drug to control BP, or hypertensive emergency.
Interventions	Exp: oral ketanserin 20 mg/day to 80 mg/day (10 women) Control: oral methyldopa 500 mg/day to 2000 mg/day (10 women)
Outcomes	Women: none reported. Babies: stillbirth, neonatal death, birthweight (mean), gestation at delivery (mean).
Notes	Interim report of study ongoing in 1987. Methods for measuring BP not mentioned. Funding: no information about funding source. Declaration of interests not described
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Not described.
Allocation concealment (selection bias)	Unclear risk	Not described: quote: "...open randomised study..." no further details.
Blinding of participants and personnel (performance bias) All outcomes	High risk	Open‐label trial.
Blinding of outcome assessment (detection bias) All outcomes	High risk	No.
Incomplete outcome data (attrition bias) All outcomes	Low risk	No.
Selective reporting (reporting bias)	Unclear risk	Assessment from published study report.
Other bias	Unclear risk	Groups appear comparable at baseline. No information about funding source. Declaration of interests not described.