France 1988a.
Methods | Allocation concealment: not stated. Authors state "random order". 3‐arm study, the two beta blocker arms were combined for the analysis. | |
Participants | 63 women at 7‐36 weeks' gestation with DBP > 90 mmHg x 2, 8 days apart). | |
Interventions | Exp: (1) oral acebutolol 400 mg to 1200 mg (21 women); (2) oral labetalol 400 mg to 1200 mg (21 women). Control: oral methyldopa 500 mg to 1500 mg (21 women). | |
Outcomes | Women: PE, caesarean section. Babies: perinatal death, preterm delivery, birthweight (mean), Apgar, admission to SCBU, hypoglycaemia. | |
Notes | No mention about Korotkoff sound considered for DBP. Main paper in French. Funding: no information about funding source. Declaration of interests not described. |
|
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Quote: "Apres tirage au sort, effectué par groupe de 9 patientes..." |
Allocation concealment (selection bias) | Unclear risk | Not described. |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Open‐label trial. |
Blinding of outcome assessment (detection bias) All outcomes | High risk | No. |
Incomplete outcome data (attrition bias) All outcomes | Low risk | No. |
Selective reporting (reporting bias) | Unclear risk | Assessment from published study report. |
Other bias | Unclear risk | Groups appear comparable at baseline. No information about funding source. Declaration of interests not described. |