India 1992.

Methods	Allocation concealment: not stated. Authors state "randomly allocated". Two arms
Participants	30 primigravid women at 24‐37 weeks' gestation with mild‐moderate PIH (BP >/ = 140/90 mmHg x 2, 6 hrs apart). Excluded: UTI, heart disease or other cause of HT.
Interventions	Exp: oral metoprolol 50‐150 mg x 2/day. (15 women) Control: oral methyldopa 250 mg x 3/day, increased to 2000 mg/day. (15 women)
Outcomes	Women: severe HT. Babies: perinatal death, preterm delivery, gestation at delivery, birthweight, Apgar at 1 min and 5 mins (mean).
Notes	Method for measuring BP not mentioned. Funding: funded by industry.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Not described.
Allocation concealment (selection bias)	Unclear risk	Not described: quote: "...randomly allocated...". No further details.
Blinding of participants and personnel (performance bias) All outcomes	High risk	Open‐label trial.
Blinding of outcome assessment (detection bias) All outcomes	High risk	No.
Incomplete outcome data (attrition bias) All outcomes	Low risk	No.
Selective reporting (reporting bias)	Unclear risk	Assessment from published study report.
Other bias	High risk	Funded by industry.