Italy 2000.
Methods | Allocation concealment: consecutive‐numbered treatment boxes.Two arms | |
Participants | 20 women with PE (no further details). | |
Interventions | Exp: oral nifedipine GITS 30 mg/day to 60 mg/day. (10 women) Control: oral methyldopa 500 mg/day to 1000 mg/day. (10 women) | |
Outcomes | Women: BP, PE, Doppler abnormalities, need for drug adjustment, severe HT. Babies: fetal and neonatal death, preterm birth, SGA (undefined), Apgar score. | |
Notes | Published as an abstract only. Method for measuring BP not stated. Additional data provided by authors. Funding: no information about funding source. Declaration of interests not described. |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Not described. |
Allocation concealment (selection bias) | Low risk | Consecutive numbered treatment boxes provided by pharmacy (personal communication). |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Single‐blind (only for participants). |
Blinding of outcome assessment (detection bias) All outcomes | High risk | No. |
Incomplete outcome data (attrition bias) All outcomes | Low risk | No. |
Selective reporting (reporting bias) | Low risk | Additional data provided by authors. |
Other bias | Unclear risk | No information about funding source. Declaration of interests not described. |