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. 2018 Oct 1;2018(10):CD002252. doi: 10.1002/14651858.CD002252.pub4

Italy 2000.

Methods Allocation concealment: consecutive‐numbered treatment boxes.Two arms
Participants 20 women with PE (no further details).
Interventions Exp: oral nifedipine GITS 30 mg/day to 60 mg/day. (10 women)
 Control: oral methyldopa 500 mg/day to 1000 mg/day. (10 women)
Outcomes Women: BP, PE, Doppler abnormalities, need for drug adjustment, severe HT.
 Babies: fetal and neonatal death, preterm birth, SGA (undefined), Apgar score.
Notes Published as an abstract only. Method for measuring BP not stated. Additional data provided by authors.
Funding: no information about funding source.
Declaration of interests not described.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Not described.
Allocation concealment (selection bias) Low risk Consecutive numbered treatment boxes provided by pharmacy (personal communication).
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Single‐blind (only for participants).
Blinding of outcome assessment (detection bias) 
 All outcomes High risk No.
Incomplete outcome data (attrition bias) 
 All outcomes Low risk No.
Selective reporting (reporting bias) Low risk Additional data provided by authors.
Other bias Unclear risk No information about funding source. Declaration of interests not described.