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. 2018 Oct 1;2018(10):CD002252. doi: 10.1002/14651858.CD002252.pub4

USA 2016a.

Trial name or title Efficacy of Sildenafil in preterm preeclampsia (SIL). ClinicalTrials.gov Identifier: NCT02782559
Methods Double‐blind, placebo‐controlled RCT.
Participants Target: 44.
Hospitalised patients of gestational age of ≥ 24 0/7 weeks to ≤ 32 0/7 weeks; dating of pregnancy by ultrasound < or equal to 22 weeks or IVF conception and diagnosis of preterm pre‐eclampsia or superimposed pre‐eclampsia.
Interventions Treatment arm: sildenafil 40 mg oral tablet 3 times a day from randomisation until delivery.
Control arm: matched to oral capsule of active treatment 3 times a day from randomisation until delivery.
Outcomes Primary outcomes: duration of pregnancy from diagnosis/randomisation until delivery.
Secondary outcomes: not reported.
Starting date July 2016
Contact information The University of Texas Health Science Center, Houston ‐ USA
Contact: Robyn P Roberts, MD (734‐934‐4227) Robyn.P.Roberts@uth.tmc.edu
 Contact: Maria Hutchinson (713‐500‐0510) Maria.S.keefer@uth.tmc.edu
Notes Ongoing.