TABLE 1.
Patient and transfusiona characteristics (N = 678 subjects)
| Characteristic | All Patients | Massively Transfused (n=313) |
Non-Massively Transfused (n=365) |
|---|---|---|---|
| Age (years), median (IQR) | 34 (25–51) | 33 (24–52) | 35 (25–50) |
| Male sex, No. (%) | 541 (80.5) | 251 (80.2) | 293 (80.3) |
| Race, No. (%) | |||
| White | 432 (63.7) | 200 (63.9) | 232 (63.6) |
| Black | 186 (27.4) | 86 (27.5) | 100 (27.4) |
| Other | 60 (8.9) | 27 (8.6) | 33 (9.0) |
| Mechanism of injury, No. (%) | |||
| Blunt | 350 (51.6) | 174 (55.6) | 176 (48.2) |
| Penetrating | 320 (47.2) | 135 (43.1) | 185 (50.7) |
| Both | 8 (1.2) | 4 (1.3) | 4 (1.1) |
| Injury Severity Score, median (IQR) | 26 (17–41) | 33 (22–42) | 24 (14–34) |
| Revised Trauma Score, median (IQR) - n=605 | 6.8 (4.1–7.8) | 6.4 (4.1–7.6) | 6.9 (4.1–7.8) |
| Glasgow Coma Scale score, median (IQR) | 14 (3–15) | 13 (3–15) | 14 (3–15) |
| Systolic blood pressure (mm Hg), median (IQR) - n=656 | 102 (80–126) | 100 (80–126) | 104 (82–126) |
| Diastolic blood pressure (mm Hg), median (IQR) - n=561 | 70 (51–91) | 70 (50–91) | 70 (53–91) |
| Heart rate (beats per minute), median (IQR) – n=675 | 114 (94–133) | 121 (98–139) | 110 (93–127) |
| Respiratory rate (breaths per minute), median (IQR) – n=619 | 20 (17–26) | 20 (17–27) | 20 (18–26) |
| Total PRBCs transfused for all patients (n) | 8,830 units | 6,776 units | 2,054 units |
| PRBC unit age (days), median (IQR) | 19 (13–27) | 20 (16–26) | 19 (14–26) |
| Total PRBC units per subject (n), median (IQR) | 9 (5–15); min 1, max 115 |
17 (12–25); min 5, max 115 |
6 (4–7); min 1, max 9 |
| Total 0–7 day old PRBC units per subject (n), median (IQR) | 3 (2–5); min 1, max 38 | 0 (0–2); min 0, max 38 |
0 (0–0); min 0, max 8 |
| Total 8–14 day old PRBC units per subject (n), median (IQR) | 4 (2–7); min 1, max 58 | 3 (0–7); min 0, max 58 |
1 (0–1); min 0, max 9 |
| Total 15–21 day old PRBC units per subject (n), median (IQR) | 3 (2–6); min 1, max 35 | 3 (0–8); min 0, max 56 |
1 (0–2); min 0, max 8 |
| Total 22+ day old PRBC units per subject (n), median (IQR) | 5 (3–10); min 1, max 69 |
6 (2–12); min 0, max 69 |
1 (0–3); min 0, max 9 |
| Total PRBC units per study site (n), median (IQR) | 647.5 (499.5–795.0); min 230, max 2017 |
469.5 (350.5–583.0); min 150, max 1682 |
142 (98.5–260.0); min 76, max 335 |
a
Data reflect PRBCs transfused in the first 24 hours of treatment. All PRBCs given in the PROPPR trial were stored in one of three additive solutions. All solutions available in the United States and Canada have equivalent storage durations [29]. PRBC = packed red blood cells. IQR = interquartile range. Numbers may not equal 100% due to missing data.