Skip to main content
. 2018 Oct 15;2018(10):CD011687. doi: 10.1002/14651858.CD011687.pub2

Schwenk 2015.

Study characteristics
Methods Study design: randomised controlled trial
Study grouping: parallel group
Participants Baseline characteristics
Usual care
  • Age (yr): 71.82 (SD 8.85)

  • Number of women (%): 6 (54.4)


Exercise
  • Age (yr): 68.73 (SD 8.72)

  • Number of women (%): 7 (63.6)


Inclusion criteria: aged ≥ 55 years; able to provide written consent; diagnosis of current or previous cancer; ability to walk to 10 m without assistive device; presence of chemotherapy‐induced peripheral neuropathy as confirmed by symptoms (numbness, tingling or pain) and signs (reduced vibration perception threshold > 25 V)
Excluded criteria: diabetes, foot ulcers or infection; neurological issues (e.g. Parkinson's disease, stroke or multiple sclerosis); severe visual impairment
Group differences: none
Interventions Usual care
  • Asked not to change their physical activity during the study


Exercise
  • 2 × 45 minutes × 4 weeks of balance training

Outcomes Medio‐lateral sway – eyes open
  • Outcome type: continuous

  • Reporting: full

  • Scale: distance

  • Unit of measure: centimetres

  • Direction: lower was better

  • Data value: change from baseline

Identification Sponsorship source: Flinn Foundation, and National Institute on Aging
Country: USA
Setting: University of Arizona Cancer Center
Comments: none
Author's name: Michael Schwenk
Institution: Interdisciplinary Consortium on Advanced Motion Performance, University of Arizona
E‐mail: schwenk.michael@gmail.com
Address: 1501 N Campbell Ave, AHSC 4303D, Tucson, AZ, USA
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Participants were randomly assigned to groups after completion of baseline measurements by a person unrelated to the study using the urn design
Allocation concealment (selection bias) Low risk Randomisation was conducted by a person not involved in the study after baseline measurements were completed
Blinding of participants and personnel (performance bias)
All outcomes High risk Participants were not blinded to their allocation
Blinding of outcome assessment (detection bias) Low risk Investigators were unaware of group allocation
Incomplete outcome data (attrition bias)
All outcomes Low risk Missing outcome data described
Selective outcome reporting (reporting bias) Low risk Outcome data checked against protocol registered with ClinicalTrials.gov
Size of study High risk Fewer than 50 participants per treatment arm
Other sources of bias Low risk Study appeared free of other sources of bias