8. Suggested design of study.

Methods	Allocation: randomised, fully explicit description of methods of randomisation and allocation concealment. Blinding: single, tested. Setting: community rather than hospital. Duration: 12 weeks treatment, and then follow‐up to at least 52 weeks.
Participants	Diagnosis: schizophrenia (ICD). N = 300.* Age: adults. Sex: both.
Interventions	1. Cognitive behaviour therapy plus standard care. N = 150. Content: a discrete psychological intervention, which is in addition to, and separate from, other therapeutic interventions (for example, behavioural family therapy) and recipients establish links between their symptoms, thoughts and beliefs, and consequent distress or problem behaviour, and the re‐evaluation of their perceptions, beliefs or reasoning relating to the target symptoms; this may include the re‐evaluation of specific 'inferential' beliefs or more global 'evaluative' beliefs. Delivered by: experienced therapists. 2. Other psychosocial therapy plus standard care . N = 150.
Outcomes	General: time to all‐cause treatment failure marked by its discontinuation, relapse/rehospitalisation, general impression of clinician (CGI), carer/other, compliance with treatment. Mental state: BPRS and PANSS. Global state: CGI (Clinical Global Impression). Quality of life. QOL (Quality of Life Questionnaire). Social functioning: return to everyday living for 80% of time.* Economic outcomes.
Notes	* Powered to be able to identify a difference of ˜ 20% between groups for primary outcome with adequate degree of certainty.

BPRS = Brief Psychiatric Rating Scale
 CGI = 
 ICD = International Classification of Diseases
 PANSS = Positive and Negative Syndrome Scale
 QOL =