Chen 2014.
Methods | Allocation: randomised Blinding: not reported Location: inpatients, China Length of follow‐up: 8 weeks |
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Participants | Diagnosis: schizophrenia with depression (CCMD‐3) N = 90 Sex: 44 M, 46 F Age: 24 ‐ 51 years Included: length of illness: not stated; achieved clinical response (the decrease rate of PANSS total score ≥ 50% or PANSS total score ≤ 60) after drug therapy Excluded: participants combined with mental retardation or drug abuse; participants with bipolar disorder; participants with severe physical disorder or severe brain organic disorder; suicidal attempts |
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Interventions | 1. CBT group*: N = 45 Content: psychoeducation; help for participants to figure out their inappropriate beliefs and attitude; help for participants to recognise their cognitive problems and rebuild their personality and behaviour; psychoeducation to families Delivered by: not reported Frequency: 30 minutes each session; once per week for 8 weeks Treatment duration: 8 weeks 2. Standard care group: N = 45 Content: received usual nursing care and antipsychotics Treatment duration: 8 weeks |
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Outcomes | Mental state: depression (HAMD score) Satisfaction with treatment: leaving the study early Engagement with services: compliance to medication |
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Notes | * Participants in CBT group also received the standard care intervention. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Quote: "Participants were randomly assigned..." (p.85). Comments: insufficient information about the sequence generation process to permit judgement of 'Low risk' or 'High risk' |
Allocation concealment (selection bias) | Unclear risk | Comments: The method of concealment was not described. |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Comments: The method of blindness was not described. It was likely that the blinding could have been broken, because participants in the treatment group received CBT. |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Comments: The method of blindness was not described. |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Comments: Eight participant from the CBT group and seven participants from the antipsychotic and nursing group failed to complete the trial. No reasons were reported. |
Selective reporting (reporting bias) | Low risk | Comments: All measured outcomes were reported. |
Other bias | Low risk | Comments: none obvious |