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. 2018 Dec 20;2018(12):CD007964. doi: 10.1002/14651858.CD007964.pub2

Li 2015a.

Methods Allocation: randomised
Blinding: not addressed
Location: community care, China
Length of follow‐up: 1 year
Participants Diagnosis: chronic schizophrenia (CCMD‐3)
N = 100
Sex: 48 M, 44 F
Age: 18 ‐ 60 years, mean ˜ 37.3 years, SD ˜ 10 years
Included: length of illness: mean ˜ 14 years, SD ˜ 10.9 years; length of illness > 5 years, state of the illness was stabilised and medication was continued, living in community and taken care by at least one of the direct relatives
Excluded: mental retardation, serious physical disease, pregnancy or lactation
Interventions 1. CBT group*: N = 48
Content: functional analysis of symptoms and negative behaviour, providing treatment therapy, to help participants to develop positive attitudes, improve cognitive abilities, reduce conflicts with social interaction, improve clinical compliance, reduce negative mood, improve the way of thinking
Delivered by: specially trained therapists
Frequency: A 50‐minute CBT was conducted twice weekly in the first 6 months, once per week in the next 6 months, with a specialist coming weekly in assistance with the therapies.
Treatment duration: 1 year
2. Standard care group**: N = 44
Content: not reported
Delivered by: not reported
Frequency: not reported
Treatment duration: 1 year
Outcomes Mental state: general (SCL‐90 scores)
Satisfaction with treatment: leaving the study early
Unable to use:
Mental state: depression, anxiety, psychotic symptoms, somatisation, sensitivity of interpersonal relationships, obsessive‐compulsive disorder, hostility, paranoia, phobia (SCL‐90 scores) ‐ skewed data
Burden: family burden scale score for relatives of the participant (not predefined outcome for this review)
Notes *Participants in the CBT group also received the standard care intervention.
**The term 'Control' was used for the comparator group with no further details given.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Quote: "Randomisation was carried out by using random number table." (p.2)
Comments: The investigators described a random component in the sequence generation process.
Allocation concealment (selection bias) Unclear risk Comments: The author did not describe allocation concealment. Insufficient information to permit judgement of 'Low risk' or 'High risk'
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Comments: The author did not describe the blinding of participants and personnel. However, as the CBT was based on standard care, participants and personnel were not likely to be blinded.
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Comments: The author did not describe the blinding of outcome assessment. Insufficient information to permit judgement of 'Low risk' or 'High risk'.
Incomplete outcome data (attrition bias) 
 All outcomes Low risk Comments: 2 participants in the CBT group and 6 participants in the standard care group dropped out during the study, due to the participants or relatives refusing treatment.
Selective reporting (reporting bias) Low risk Comments: All measured outcomes were reported.
Other bias Low risk Comments: none obvious. The study was funded by Chang Zhou scientific project funding from the Department of Science and Technology of Jiangsu province, no. CS20102013.