Wang 2015.
Methods | Allocation: randomised Blinding: not addressed Location: inpatients, China Length of follow‐up: 64 weeks |
|
Participants | Diagnosis: schizophrenia (ICD‐10) N = 32 Sex: 17 M, 15 F Age: mean ˜ 39.9 years, SD ˜ 11.4 years Included: length of illness: mean ˜ 175.6 months, SD ˜ 96.9 months; at least one item score of PANSS scale ≤ 3; 18 ‐ 60 years old Excluded: admitted to hospital due to severe condition; participants combined with severe physical disorder or other mental disorder; participants received modified electroconvulsive therapy |
|
Interventions | 1. CBT group*: N = 16 Content: The intervention was based on two published cognitive behavioural therapy handbooks. Delivered by: psychologist who had been trained to conduct CBT Frequency: 8 sessions for 12 weeks, 45 to 60 minutes each session Treatment duration: 3 months 2. Standard care group: N = 16 Content: antipsychotics, case management, entertainment therapy, social support, and psychoeducation Delivered by: not reported Frequency: not reported Treatment duration: 3 months |
|
Outcomes | Global state: relapse, clinically important change (no improvement)**, (CGI scores) Mental state: general, positive symptoms, negative symptoms, affective symptoms (PANSS scores) Functioning: social function (PSP scores) Quality of life: general (WHOQOL‐BREF scores) Satisfaction with treatment: leaving the study early |
|
Notes | *Participants in the CBT group also received the standard care intervention. **Defined as the score of CGI‐GI more than 2 |
|
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Quote: "Participants were randomly assigned..." (p.17). Comments: insufficient information about the sequence generation process to permit judgement of 'Low risk' or 'High risk' |
Allocation concealment (selection bias) | Unclear risk | Comments: The method of concealment was not described. |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Comments: The author did not address this information. However, participants and personnel were not likely to be blinded because participants in the treatment group received CBT, and the control group only received standard care. |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Comments: The method of blindness was not described. |
Incomplete outcome data (attrition bias) All outcomes | Low risk | Comments: Two participants left the study early; one from each group before intervention. Low proportion of dropouts. |
Selective reporting (reporting bias) | Low risk | Comments: All measured outcomes were reported. |
Other bias | Low risk | Comments: none obvious |