Skip to main content
. 2018 Dec 20;2018(12):CD007964. doi: 10.1002/14651858.CD007964.pub2

Zhao 2013.

Methods Allocation: randomised
Blinding: not addressed
Location: inpatients, China
Length of follow‐up: 8 weeks
Participants Diagnosis: schizophrenia (CCMD‐3)
N = 100
Sex: 33 M, 65 F
Age: 18 ‐ 60 years, mean ˜ 36 years, SD ˜ 7 years
Included: length of illness: mean ˜ 6.2 years, SD ˜ 3.5 years; schizophrenia (CCMD‐3)
Excluded: mental retardation; dementia or other brain organic disease; severe physical disorder
Interventions 1. CBT group*: N = 50
Content: psychoeducation about symptoms and coping strategies for symptoms; cognition modification, and encouragement of social intercourse
Delivered by: five psychologists
Frequency: 45‐minute session, one or two sessions per week for 4 weeks, three sessions or four sessions per month after 4 weeks
Treatment duration: 8 weeks
2. Standard care group: N = 50
Content: antipsychotics
Delivered by: not reported
Frequency: not reported
Treatment duration: 8 weeks
Outcomes Mental state: clinically important change (no improvement)**, general (BPRS scores)
Satisfaction with treatment: leaving the study early
Unable to use:
Social support (not predefined outcome for this review)
Notes *Participants in the CBT group also received the standard care intervention.
**Defined as reduction in BPRS score < 30%
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Quote: "Participants were randomly assigned..." (p.117).
Comments: insufficient information about the sequence generation process to permit judgement of 'Low risk' or 'High risk'
Allocation concealment (selection bias) Unclear risk Comments: The method of concealment was not described.
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Comments: The author did not address this information. However, participants and personnel were not likely to be blinded because participants in the treatment group received CBT, and the control group only received standard care.
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Comments: The method of blindness was not described.
Incomplete outcome data (attrition bias) 
 All outcomes Low risk Comments: Two participants in the control group dropped out from the study, with no reasons reported. It was not possible that the low proportion of missing dataaffected the intervention effect estimate.
Selective reporting (reporting bias) Low risk Comments: All measured outcomes were reported.
Other bias Low risk Comments: none obvious