Zhao 2013.
Methods | Allocation: randomised Blinding: not addressed Location: inpatients, China Length of follow‐up: 8 weeks |
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Participants | Diagnosis: schizophrenia (CCMD‐3) N = 100 Sex: 33 M, 65 F Age: 18 ‐ 60 years, mean ˜ 36 years, SD ˜ 7 years Included: length of illness: mean ˜ 6.2 years, SD ˜ 3.5 years; schizophrenia (CCMD‐3) Excluded: mental retardation; dementia or other brain organic disease; severe physical disorder |
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Interventions | 1. CBT group*: N = 50 Content: psychoeducation about symptoms and coping strategies for symptoms; cognition modification, and encouragement of social intercourse Delivered by: five psychologists Frequency: 45‐minute session, one or two sessions per week for 4 weeks, three sessions or four sessions per month after 4 weeks Treatment duration: 8 weeks 2. Standard care group: N = 50 Content: antipsychotics Delivered by: not reported Frequency: not reported Treatment duration: 8 weeks |
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Outcomes | Mental state: clinically important change (no improvement)**, general (BPRS scores) Satisfaction with treatment: leaving the study early Unable to use: Social support (not predefined outcome for this review) |
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Notes | *Participants in the CBT group also received the standard care intervention. **Defined as reduction in BPRS score < 30% |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Quote: "Participants were randomly assigned..." (p.117). Comments: insufficient information about the sequence generation process to permit judgement of 'Low risk' or 'High risk' |
Allocation concealment (selection bias) | Unclear risk | Comments: The method of concealment was not described. |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Comments: The author did not address this information. However, participants and personnel were not likely to be blinded because participants in the treatment group received CBT, and the control group only received standard care. |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Comments: The method of blindness was not described. |
Incomplete outcome data (attrition bias) All outcomes | Low risk | Comments: Two participants in the control group dropped out from the study, with no reasons reported. It was not possible that the low proportion of missing dataaffected the intervention effect estimate. |
Selective reporting (reporting bias) | Low risk | Comments: All measured outcomes were reported. |
Other bias | Low risk | Comments: none obvious |