| Methods |
Unicentre, randomized, controlled study |
| Participants |
Setting: San Gerardo Hospital in Milan, Italy
Inclusion criteria: Adults at least 18 years old eligible for enrolment if they were expected to require mechanical ventilation with an endotracheal tube with an internal diameter of 7.5 mm or 8.0 mm for 48 hours or longer
Exclusion criteria: Males and females less than 18 years old; patients who are expected to be intubated for less than 48 hours; patients who are allergic to silver‐sulfadiazine; patients who require an endotracheal tube with an internal diameter less than 7.5 mm or greater than 8.0 mm; patients who do not tolerate disconnection from the ventilator; haemodynamically unstable; severe ARDS: PaO2/FiO2 ≤ 200 at PEEP ≤ 5 cmH20
Participant numbers: not mentioned |
| Interventions |
Silver‐sulfadiazine tracheal tubes/mucus shaver in intubated patients expected to have a prolonged mechanical ventilation |
| Outcomes |
No outcome data were available |
| Notes |
|
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
No outcome data were available to judge this bias |
| Allocation concealment (selection bias) |
Unclear risk |
No outcome data were available to judge this bias |
| Blinding of participants and personnel (performance bias)
All outcomes |
Unclear risk |
No outcome data were available to judge this bias |
| Blinding of outcome assessment (detection bias)
All outcomes |
Unclear risk |
No outcome data were available to judge this bias |
| Incomplete outcome data (attrition bias)
All outcomes |
Unclear risk |
No outcome data were available to judge this bias |
| Selective reporting (reporting bias) |
Unclear risk |
No outcome data were available to judge this bias |
| Other bias |
High risk |
Possible publication bias |
