2. Table of secondary outcomes.

Study	Protocolized weaning		Non‐protocolized weaning
	N	Mean (SD)	N	Mean (SD)	Mean difference	95% CI	P‐value
Duration of mechanical ventilation before weaning (hours)
Jouvet 2013	15	157 (189)	15	141 (104)	‐16	‐125.17 to 93.17	0.89
Maloney 2007	15	74.5 (39.3)*	16	84 (53.3)*	9.5	‐23.33 to 42.33	0.50
Weaning duration (hours)
Jouvet 2013	15	36 (36)	15	142 (150)	106	27.94 to 184.06	0.007
Maloney 2007	15	8 (9.3)*	16	28.5 (22.2)*	20.5	8.65 to 32.35	<0.001
PICU length of stay (hours)
Jouvet 2013	15	216 (120)	15	696 (504)	480	217.82 to 742.18	0.11
Maloney 2007	15	176 (64)	16	217 (114)	41	‐23.57 to 105.57	0.23
Hospital length of stay (hours)
Jouvet 2013	15	648 (432)	15	696 (504)	48	‐287.93 to 383.93	0.68
Maloney 2007	15	312 (88)	16	436 (338)	124	‐47.50 to 295.50	0.18

* Standard deviation approximated from the interquartile range.