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. 2018 Jul 17;104(7):2473–2489. doi: 10.1210/jc.2018-00688

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This article has been published under the terms of the Creative Commons Attribution License (CC BY; https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Copyright for this article is retained by the author(s).

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Figure 6. — Silent corticotroph adenoma: noninvasive macroadenoma. (A) Axial contrast-enhanced T1-weighted sequence. (B) Histologic slide showing sheets and acini with uniform, medium-size cells with basophilic cytoplasm (hematoxylin and eosin stain, ×20). (C) Expression of ACTH is diffuse (immunoperoxidase stain, ×10). (D) Neoplastic cells show nuclear expression of the transcription factor TPIT (immunoperoxidase stain, ×10). (E) No expression of PC1/3 was present in the tumor cells (immunoperoxidase stain, ×10).