| Methods |
Single‐centre RCT (Turkey) |
| Participants |
Adult participants over 18 years old needing a CVC for TPN. Patients who were estimated to need a CVC for less than 3 days, allergic to silver sulphadiazine, burn patients or those with skin lesions at the catheterization area and pregnant women were excluded |
| Interventions |
C‐SS‐impregnated CVCs versus non‐impregnated CVCs |
| Outcomes |
Catheter colonization and CRBSI |
| Notes |
Article was in Turkish and the information was obtained through a translation. Sources of funding: not stated |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
The authors stated that the 2 groups were randomly assigned to receive the study and control catheters, but no further details were given about the methods of sequence generation |
| Allocation concealment (selection bias) |
Unclear risk |
There was no information available that would enable an assessment of whether random sequence was generated independently from allocation |
| Blinding of participants and personnel (performance bias)
All outcomes |
High risk |
There were no clear statements about blinding, although blinding appeared unlikely as the 2 types of CVCs differed in appearance and there was no mention of any measures taken to blind those involved in the study |
| Blinding of outcome assessment (detection bias)
Microbiological outcomes like catheter colonization |
Unclear risk |
It was unclear whether the microbiological outcome assessors were blinded |
| Blinding of outcome assessment (detection bias)
Clinical outcomes like CRBSI |
High risk |
There were no clear statements about blinding, although blinding appeared unlikely as the 2 types of CVCs used differed in appearance and there was no mention of any measures taken to blind those involved in the study |
| Incomplete outcome data (attrition bias)
All outcomes |
Low risk |
The authors stated in the Methods that they would enrol 30 participants in this study. In the Results, a total of 30 participants (13 in the study group and 17 in the control group) were analyzed, suggesting that there was no loss of follow‐up in this study |
| Selective reporting (reporting bias) |
Low risk |
The 2 major outcomes specified in the Methods, namely, catheter colonization and CRBSI, were reported in sufficient detail in the Results |
| Other bias |
Low risk |
None identified |
